CROHN’S DISEASE: L’IMPATTO DELL’APPROCCIO CON IMMUNOSOPPRESSORI ED ANTI-TNF NEL POST-OPERATORIO IN UNO STUDIO MULTICENTRICO DI “REAL WORLD”, COORDINATO DAL S. FILIPPO NERI DI ROMA. DA”ALIMENTARY PHARMACOLOGY & THERAPEUTICS”

CHIRURGIA, GASTROENTEROLOGIA, IBD, NEWSLETTER, REAL WORLD EVIDENCE, Senza categoria

Crohn’s disease after surgery: Changes in post-operative management strategies over time and their impact on long-term re-operation rate—A retrospective multicentre real-world study Annalisa Aratari et al. Summary Background Few data are available addressing the impact of post-operative management of Crohn’s disease (CD) on long-term clinical course. Aim To assess the evolution of post-operative management strategies…

CROHN’S DISEASE: L’APPROCCIO TOP-DOWN E’ SUPERIORE ALLO STEP-UP ! “PROFILE” : UN GRANDE TRIAL RANDOMIZZATO MULTICENTRICO. DA “LANCET GASTROENTEROLOGY & HEPATOLOGY” (FREE)

GASTROENTEROLOGIA, IBD, NEWSLETTER, Senza categoria

A biomarker-stratified comparison of top-down versus accelerated step-up treatment strategies for patients with newly diagnosed Crohn’s disease (PROFILE): a multicentre, open-label randomised controlled trial Nurulamin M Noor, et al. Summary Background Management strategies and clinical outcomes vary substantially in patients newly diagnosed with Crohn’s disease. We evaluated the use of a putative prognostic biomarker to…

ISCHEMIA MESENTERICA CRONICA: MEGLIO LE PROTESI COPERTE ! UN DIFFICILE GRANDE TRIAL OLANDESE DA “LANCET GASTROENTEROLOGY & HEPATOLOGY”

DIAGNOSTICA PER IMMAGINI, GASTROENTEROLOGIA, MEDICINA INTERNA, Senza categoria

Covered versus bare-metal stenting of the mesenteric arteries in patients with chronic mesenteric ischaemia (CoBaGI): a multicentre, patient-blinded and investigator-blinded, randomised controlled trial Luke G Terlouw et al.† Summary Background Mesenteric artery stenting with a bare-metal stent is the current treatment for atherosclerotic chronic mesenteric ischaemia. Long-term patency of bare-metal stents is unsatisfactory due to…

EPATOCARCINOMA: LE NUOVE LINEE GUIDA INGLESI 2024. DA “GUT” (FREE)

CHIRURGIA, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults   Abid Suddle et al. Abstract Deaths from the majority of cancers are falling globally, but the incidence and mortality from hepatocellular carcinoma (HCC) is increasing in the United Kingdom and in other Western countries. HCC is a highly fatal cancer, often…

PANCREATECTOMIA DISTALE: MEGLIO NON INSERIRE DRENAGGIO PROFILATTICO ? UN TRAL RANDOMIZZATO MULTICENTRICO OLANDESE-ITALIANO. DA “LANCET GASTROENTEROLOGY&HEPATOLOGY”

CHIRURGIA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

Prophylactic abdominal drainage after distal pancreatectomy (PANDORINA): an international, multicentre, open-label, randomised controlled, non-inferiority trial Eduard A van Bodegraven et al Summary Background Prophylactic passive abdominal drainage is standard practice after distal pancreatectomy. This approach aims to mitigate the consequences of postoperative pancreatic fistula (POPF) but its added value, especially in patients at low risk…

GESTIONE DELLA DIVERTICOLITE ACUTA: UNA OTTIMA REVISIONE 2024 PER GASTROENTEROLOGI E CHIRURGHI. DA “JAMA SURGERY” (FREE).

CHIRURGIA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

Management of Diverticulitis. A Review Olivia A. Sacks, MD1,2; Jason Hall, MD, MPH3 Abstract Importance  Care of patients with diverticulitis is undergoing a paradigm shift. This narrative review summarizes the current evidence for left-sided uncomplicated and complicated diverticulitis. The latest pathophysiology, advances in diagnosis, and prevention strategies are also reviewed. Observations  Treatment is moving to the outpatient setting, physicians are forgoing antibiotics…