APPENDICITE ACUTA NON COMPLICATA. ANTIBIOTICI PER OS SONO EQUIVALENTI AD ANTIBIOTICI ENDOVENA. I DATI A 3 ANNI DI UN AMPIO TRIAL FINLANDESE. DA “JAMA SURGERY” (FREE)

CHIRURGIA, GASTROENTEROLOGIA, MEDICINA INTERNA, NEWSLETTER, Senza categoria

Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute AppendicitisA Secondary Analysis of the APPAC II Randomized Clinical Trial Liisa Selänne et al. Key PointsQuestion  What are the long-term treatment outcomes of oral antibiotics alone compared with a combination of intravenous (IV) and oral antibiotics for computed tomography–confirmed uncomplicated acute appendicitis? Findings  In this…

URCA! LA POSITIVITA’ ALL’HELICOBACTER PYLORI AUMENTA ANCHE L’INCIDENZA E LA MORTALITA’ DEL CANCRO DEL COLON! UNO STUDIO DI COORTE AMERICANO DA “J. OF CLINICAL ONCOLOGY”

CHIRURGIA, ENDOSCOPIA, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, NEWSLETTER, ONCOLOGIA, Senza categoria

Impact of Helicobacter pylori Infection and Treatment on Colorectal Cancer in a Large, Nationwide Cohort  Shailja C. Shah, et al. Abstract Purpose Helicobacter pylori is the most common cause of infection-associated cancer worldwide. We aimed to evaluate the impact of H. pylori infection and treatment on colorectal cancer (CRC) incidence and mortality. Patients US Veterans who…

ERCP: SI’, E’ MEGLIO FARE L’ANTIBIOTICO (UNA CEFALOSPORINA) PRIMA DELLA ESECUZIONE IN CASO DI UNA OSTRUZIONE BILIARE. UN TRIAL MULTICENTRICO DA”AJG” (FREE).

DIAGNOSTICA PER IMMAGINI, ECOGRAFIA ED ECOENDOSCOPIA, ENDOSCOPIA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

Randomized Trial of Prophylactic Antibiotics for Endoscopic Retrograde Cholangiopancreatography in Patients With Biliary Obstruction Leem, Galam et al. Abstract INTRODUCTION: The incidence of postendoscopic retrograde cholangiopancreatography (ERCP) infections is reported to be up to 18% in patients with biliary obstruction. Antibiotic prophylaxis may reduce the risk of infectious complications after ERCP; however, the clinical value…

EMORRAGIA DA ULCERA: E’ MEGLIO METTERE LA CLIP CON LA TECNICA “OVER-THE-SCOPE” CHE CON L’APPROCCIO “THROUGH-THE-SCOPE”. UN TRIAL MULTICENTRICO ITALIANO DA “ENDOSCOPY”

CHIRURGIA, ENDOSCOPIA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

Over-the-scope clip as first-line treatment of peptic ulcer bleeding: a multicentre randomized controlled trial (TOP Study) Paola Soriani et al. Background: First-line over-the-scope-clip (OTSC) treatment has shown higher efficacy than standard endoscopic therapy in acute non-variceal upper gastrointestinal bleeding (UGIB) from different causes. We performed a head-to-head randomized controlled trial (RCT) comparing OTSC vs through-the-scope-clip…

MA QUESTO PAZIENTE HA UN DISORDINE DA ALCOL ? DA “JAMA” UNA REVISIONE DEI TEST DI SCREENING MIGLIORI ALL’ESAME OBIETTIV0. VINCE “AUDIT” !

GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NEWSLETTER, Senza categoria

Does This Patient Have Alcohol Use Disorder?The Rational Clinical Examination Systematic Review Evan Wood,  et al. Abstract Importance  The accuracy of screening tests for alcohol use disorder (defined as a problematic pattern of alcohol use leading to clinically significant impairment or distress) requires reassessment to align with the latest definition in the Diagnostic and Statistical Manual of Mental…

UN ANALOGO DELL’ORMONE FGF19, LA ALDAFERMINA, E’ UN BUON CANDIDATO PER LA NASH+CIRROSI ! UN TRIAL IN DOPPIO CIECO DA “HEPATOLOGY” (FREE)

DIAGNOSTICA PER IMMAGINI, ECOGRAFIA ED ECOENDOSCOPIA, EPATOLOGIA, GASTROENTEROLOGIA, NEWSLETTER

A randomized, double-blind, placebo-controlled trial of aldafermin in patients with NASH and compensated cirrhosis Rinella, Mary E et al. Abstract Background and Aims: Aldafermin, an engineered analog of the human hormone FGF19, improves liver histology in patients with noncirrhotic NASH; however, its efficacy and safety in compensated cirrhosis is unknown. No drug has yet to…