GLI INIBITORI DELLA POMPA PROTONICA ALTERANO IL MICROBIOTA PROMUOVENDO LA TRASLOCAZIONE DI STREPTOCOCCO DALLA BOCCA. UNO STUDIO DI INTERVENTO. DA “GUT”

Proton pump inhibitors alter gut microbiota by promoting oral microbiota translocation: a prospective interventional study Xue Xiao et al. Abstract Background The mechanism by which proton pump inhibitors (PPIs) alter gut microbiota remains to be elucidated. We aimed to learn whether PPI induced gut microbiota alterations by promoting oral microbial translocation. Methods Healthy adult volunteers were randomly…

IBS: UN RUOLO PER I FARMACI CHE AGISCONO SUI RECETTORI AD ISTAMINA-1 ? ATTENSIONE. UNA META-ANALISI INGLESE MOLTO INTERESSANTE. DA “GASTROENTEROLOGY” (FREE)

Efficacy of Drugs Acting on Histamine-1 Receptors in Irritable Bowel Syndrome: Systematic Review and Meta-analysis. Mais Khasawneh, Christopher J. Black, Alexander C. Ford This meta-analysis summarizes all evidence, to date, for the use of drugs acting on histamine-1 receptors in IBS. There appear to be benefits for these types of drugs for both global symptoms…

GUIDA PER L’USO DI BIOLOGICI E “SMALL MOLECULES”. DALLA INTEGRAZIONE DELLE EVIDENZE ALLA PRATICA CLINICA ! OTTIMA ! DA “GASTROENTEROLOGY” (FREE)

Integrating Evidence to Guide Use of Biologics and Small Molecules for Inflammatory Bowel Diseases Parambir S. Dulai  et al. Advances in science have led to the development of multiple biologics and small molecules for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical therapies has been accompanied by an increase in methodological…

STATISTICA DESCRITTIVA OD INFERENZIALE ? BACK TO BASIC! DAI TUTORIAL DI “STUDENTS 4 BEST EVIDENCE” (FREE)

Descriptive vs inferential statistics: an overview Posted on 9th January 2024 by Carolina Guadalupe Cruz Muñoz Tutorials and Fundamentals ‘Biostatistics is the discipline concerned with the treatment and analysis of numerical data derived from biological, biomedical, and health-related studies’ (Gerstman B.B., 2015). Three aspects of biostatistics relevant to this blog are: Sampling, which consists of selecting…

PANCREATITE AUTOIMMUNE: UNO STUDIO EUROPEO OSSERVAZIONALE IMP0RTANTE. I TASSI DI RISPOSTA AGLI STEROIDI SONO MOLTO ELEVATI. DA “CLINICAL GASTROENTEROLOGY & HEPATOLOGY”(FREE)

Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment Kasper A. Overbeek et al. Background & Aims Autoimmune pancreatitis (AIP) is an immune-mediated disease of the pancreas with distinct pathophysiology and manifestations. Our aims were to characterize type 1 AIP in a large pan-European cohort and study the effectiveness of current treatment…

MA L’EPATOLOGIA HA ANCORA BISOGNO DELLA ENDOSCOPIA ? UNA OTTIMA REVISIONE DELLE PROCEDURE ENDOSCOPICHE (AVANZATE) IN EPATOLOGIA. DA “J. OF HEPATOLOGY” (FREE)

Endoscopic procedures in hepatology: Current trends and new developments Wim Laleman et al. Summary Gastrointestinal endoscopy has long been a reliable backbone in the diagnosis and management of hepatobilary disorders and their complications. However, with evolving non-invasive testing, personalised medicine has reframed the utility and necessity of endoscopic screening. Conversely, the growing interest and use…