MODULAZIONE DEL MICROBIOTA: UNA POTENZIALE TERAPIA PER IL CANCRO DEL PANCREAS

Therapeutic potential of microbial modulation in pancreatic cancer Vidhi Chandra and Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is an aggressive disease with a poor prognosis.1 Surgery is the only potential curative treatment, but it is only possible in patients with early-stage disease, and most patients present with non-resectable disease.1 Even in patients who undergo…

RISCHIO DI CANCRO DOPO RISCONTRO DI ADENOMA: UNA OTTIMA META-ANALISI

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review and Meta-analysis Abhiram Duvvuri et al. BACKGROUND & AIMS: The risk of metachronous colorectal cancer (CRC) among patients with no adenomas, low-risk adenomas (LRAs), or high-risk adenomas (HRAs), detected at…

NUOVE LINEE GUIDA INGLESI PER IL COLON IRRITABILE

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome Dipesh H Vasant et al. Abstract Irritable bowel syndrome (IBS) remains one of the most common gastrointestinal disorders seen by clinicians in both primary and secondary care. Since publication of the last British Society of Gastroenterology (BSG) guideline in 2007, substantial advances have…

IL CAFFE’ RIDUCE IL RISCHIO DI FIBROSI E DI CIRROSI: UNA META-ANALISI

Coffee Consumption Decreases Risks for Hepatic Fibrosis and Cirrhosis: A Meta-Analysis Fen Liu et al. Abstract Background and Aim Previous studies have demonstrated that coffee consumption may be inversely correlated with hepatic fibrosis and cirrhosis. However, the reported results have been inconsistent. To summarize previous evidences quantitatively, a meta-analysis was performed. Methods The Medline, Web…

ALIMENTI DIRETTI AL MICROBIOTA PER I BAMBINI DENUTRITI. UN TRIAL DI GRANDE IMPORTANZA

A Microbiota-Directed Food Intervention for Undernourished Children Robert Y. Chen et al. Abstract BACKGROUND More than 30 million children worldwide have moderate acute malnutrition. Current treatments have limited effectiveness, and much remains unknown about the pathogenesis of this condition. Children with moderate acute malnutrition have perturbed development of their gut microbiota. METHODS In this study,…

LE PUBBLICAZIONI “PRE-PRINT” DISTURBANO LA EBM: UN COMMENTO SULLE REVIEWS IN TEMPI DI COVID-19

Using Preprints in Evidence Synthesis: Commentary on experience during the COVID-19 pandemic Barbara Clyne  et al. Introduction SARS-CoV-2, the virus that causes COVID-19, has rapidly spread, causing millions of cases and deaths globally. Controlling the COVID-19 pandemic requires swift decision making based on initially sparse, and rapidly emerging evidence. There has been a proliferation of…