ABLAZIONE LOCALE DEL K PANCREAS. DOVE SIAMO: POCHE RISPOSTE, ANCORA MOLTE DOMANDE. UN EDITORIALE DA “LANCET GASTROENTEROLOGY&HEPATOLOGY” DOPO IL TRIAL “CROSSFIRE”

Local ablation in pancreatic cancer: some answers and more questions editorial by Zachary T Berman , Rebekah R White There is no consensus on how to treat patients with locally advanced pancreatic cancer beyond systemic chemotherapy. A minority of patients will respond well and become candidates for surgical resection, and many will die from distant disease progression.…

OCCHIO ALLA NUTRIZIONE NEI NOSTRI PAZIENTI PIU’ GRAVI! 10 RACCOMANDAZIONI DA “CRITICAL CARE” (FREE)

Personalized nutrition therapy in critical care: 10 expert recommendations Paul E. Wischmeyer et al Abstract Personalization of ICU nutrition is essential to future of critical care. Recommendations from American/European guidelines and practice suggestions incorporating recent literature are presented. Low-dose enteral nutrition (EN) or parenteral nutrition (PN) can be started within 48 h of admission. While…

GLI PSEUDO-TEST DIRETTI AL CONSUMATORE-PAZIENTE. E’ TEMPO DI MAGGIORE REGOLAMENTAZIONE. UNA IMPORTANTE NOTA DA “SCIENCE” SUI TEST PRODOTTI DA 31 COMPAGNIE!

The DTC microbiome testing industry needs more regulation Diane E. Hoffmann et al. Tests lack analytical and clinical validity, requiring more federal oversight to prevent consumer harm A growing body of research has suggested the potential for improving human health by better understanding the human microbiome. This research has led to the emergence of a…

GLI INIBITORI DELLA POMPA PROTONICA ALTERANO IL MICROBIOTA PROMUOVENDO LA TRASLOCAZIONE DI STREPTOCOCCO DALLA BOCCA. UNO STUDIO DI INTERVENTO. DA “GUT”

Proton pump inhibitors alter gut microbiota by promoting oral microbiota translocation: a prospective interventional study Xue Xiao et al. Abstract Background The mechanism by which proton pump inhibitors (PPIs) alter gut microbiota remains to be elucidated. We aimed to learn whether PPI induced gut microbiota alterations by promoting oral microbial translocation. Methods Healthy adult volunteers were randomly…

IBS: UN RUOLO PER I FARMACI CHE AGISCONO SUI RECETTORI AD ISTAMINA-1 ? ATTENSIONE. UNA META-ANALISI INGLESE MOLTO INTERESSANTE. DA “GASTROENTEROLOGY” (FREE)

Efficacy of Drugs Acting on Histamine-1 Receptors in Irritable Bowel Syndrome: Systematic Review and Meta-analysis. Mais Khasawneh, Christopher J. Black, Alexander C. Ford This meta-analysis summarizes all evidence, to date, for the use of drugs acting on histamine-1 receptors in IBS. There appear to be benefits for these types of drugs for both global symptoms…

GUIDA PER L’USO DI BIOLOGICI E “SMALL MOLECULES”. DALLA INTEGRAZIONE DELLE EVIDENZE ALLA PRATICA CLINICA ! OTTIMA ! DA “GASTROENTEROLOGY” (FREE)

Integrating Evidence to Guide Use of Biologics and Small Molecules for Inflammatory Bowel Diseases Parambir S. Dulai  et al. Advances in science have led to the development of multiple biologics and small molecules for the treatment of inflammatory bowel diseases (IBDs). This growth in advanced medical therapies has been accompanied by an increase in methodological…