Covid-19: ivermectina alla prova Pubblicato martedì 21 Settembre 2021 Sulla base delle prove attuali, non c’è sufficiente certezza sull’efficacia e la sicurezza dell’ivermectina per trattare o prevenire il covid-19. Questo in base a una revisione Cochrane di cui si è parlato molto nelle ultime settimane. L’ivermectina è un farmaco usato per trattare i parassiti, per esempio…
GRADE notes: How to use GRADE when there is “no” evidence? A case study of the expert evidence approach Reem A. Mustafa et al. Abstract Objectives One essential requirement of trustworthy guidelines is that they should be based on systematic reviews of the best available evidence. The GRADE Working Group has provided guidance for evaluating…
GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings Linan Zeng et al. Abstract Objective To provide practical principles and examples to help GRADE users make optimal choices regarding their ratings of certainty of evidence using a minimally or partially contextualized approach. Study Design and Setting Based on the…
Hypothesis Tests Explained Angelica Lo Duca A quick overview of the concept of Hypothesis Testing, its classification in parametric and non-parametric tests, and when to use the most popular ones. Image by Author What is Hypothesis Testing According to Jim Frost, Hypothesis Testing is a form of inferential statistics that allows us to draw conclusions about…
Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial Ly-Mee Yu, et al. Summary Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in patients not admitted to hospital, but effectiveness in high-risk individuals is unknown.…