Effects of Proton Pump Inhibitors on Glycemic Control and Incident Diabetes: A Systematic Review and Meta-Analysis Carol Chiung-Hui Peng et al. Abstract Context Whether proton pump inhibitors (PPI) can improve glycemic control among individuals with diabetes or decrease the risk of incident diabetes in the general population is unclear. Objective To evaluate the impact of…
Therapeutic potential of microbial modulation in pancreatic cancer Vidhi Chandra, Florencia McAllister Introduction Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDAC), is an aggressive disease with a poor prognosis.1 Surgery is the only potential curative treatment, but it is only possible in patients with early-stage disease, and most patients present with non-resectable disease.1 Even in patients who…
Statistics: Are you Bayesian or Frequentist? The fastest way to diagnose your statistical alignment Cassie Kozyrkov What if I told you that I can show you the difference between Bayesian and Frequentist statistics with one single coin toss? Before we go any further, the demonstration works best in video form, so don’t read the summary and…
How Britain Became the First Country in the World to Surrender to Covid This is What it Means to Be the Dumbest Country in the World Umair Haque You might have long thought America — or your country — was the dumbest in the world. Ah, my friend. Here’s a situation so surreal that it’s…
How to use likelihood ratios to interpret evidence from randomized trials Thomas V.Perneger Highlights • The likelihood ratio represents evidence from a study about the relative merits of two hypotheses – typically, in a clinical trial, the hypotheses that the new treatment is effective (at a specific level), vs. that it is not. • The likelihood…
Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway: population based cohort study Anton Pottegård et al. Objective To assess rates of cardiovascular and haemostatic events in the first 28 days after vaccination with the Oxford-AstraZeneca vaccine ChAdOx1-S in Denmark and Norway and to compare them with rates…