LA DIETA PREBIOTICA (INULINA) MIGLIORA LE COMUNICAZIONI BRAIN-GUT VIA MICROBIOMA IN PAZIENTI SOVRAPPESO. UNO SPLENDIDO TRIAL CROSS-OVER TEDESCO. DA “GUT” (FREE)

MEDICINA DEI PROBIOTICI, NEWSLETTER, NUTRIZIONE, Senza categoria

Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial Evelyn Medawar et al. Abstract Objective Animal studies suggest that prebiotic, plant-derived nutrients could improve homoeostatic and hedonic brain functions through improvements in microbiome–gut–brain communication. However, little is known if these results are applicable to humans. Therefore, we tested the…

POLIPECTOMIA DI ADENOMI NON PEDUNCOLATI DEL COLON: RESEZIONE “EN BLOC” E’ SUPERIORE ALL’APPROCCIO “PIECEMEAL”. UN OTTIMO TRIAL FRANCESE MULTICENTRICO, DA”ANNALS OF INTERNAL MEDICINE”

ENDOSCOPIA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

Endoscopic En Bloc Versus Piecemeal Resection of Large Nonpedunculated Colonic Adenomas A Randomized Comparative Trial Jérémie Jacques et al. Abstract Background: Endoscopic resection of adenomas prevents colorectal cancer, but the optimal technique for larger lesions is controversial. Piecemeal endoscopic mucosal resection (EMR) has a low adverse event (AE) rate but a variable recurrence rate necessitating…

L’USO DI ANTIBIOTICI E’ FATTORE DI RISCHIO PER LO SVILUPPO DI IBD (+28-54%): UNO STUDIO DI POPOLAZIONE DANESE. DA “GUT” (FREE)

GASTROENTEROLOGIA, IBD, NEWSLETTER, Senza categoria

Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study Adam S Faye et al. Abstract Background There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors are suspected. Antibiotics have been associated with development of IBD in earlier generations, but their influence on IBD…

LA TERAPIA CON BIOLOGICI PER LE IBD. L’IMPATTO DELLA SEQUENZA TERAPEUTICA NELLO STUDIO INGLESE DI REAL-WORLD IN 13.222 PAZIENTI. IL RUOLO DEL VEDOLIZUMAB. DA”J Crohns Colitis”.

CHIRURGIA, ENDOSCOPIA, GASTROENTEROLOGIA, IBD, NEWSLETTER, REAL WORLD EVIDENCE, Senza categoria

Biologic therapy for inflammatory bowel disease: Real-world comparative effectiveness and impact of drug sequencing in 13,222 patients within the UK IBD BioResource Christina Kapizion et al. Abstract Background and aims: To compare effectiveness of different biologic therapies and sequences in patients with Inflammatory Bowel Disease (IBD) using real-world data from a large cohort with long exposure.…

ASPIRINA E PREVENZIONE DEL CANCRO. LA RECENTISSIMA REVISIONE DELLE REVISIONI E META-ANALISI! PRO E CONTRO. DA “british journal of cancer” (FREE)

EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NEWSLETTER, ONCOLOGIA, Senza categoria

Aspirin and cancer treatment: systematic reviews and meta-analyses of evidence: for and against Peter Elwood et al. Abstract Aspirin as a possible treatment of cancer has been of increasing interest for over 50 years, but the balance of the risks and benefits remains a point of contention. We summarise the valid published evidence ‘for’ and…

FARMACOTERAPIA PER LA DIPENDENZA DA ALCOL: OCCHIO A NALTREXONE ED AL ACAMPROSATO! UNA OTTIMA META-ANALISI. DA “JAMA”

EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NEWSLETTER, NUTRIZIONE, Senza categoria

Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis Melissa McPheeters et al Key Points Question  Which pharmacotherapies are associated with improved outcomes for people with alcohol use disorder? Findings  In this systematic review and meta-analysis that included 118 clinical trials and 20 976 participants, 50 mg/d of oral naltrexone and acamprosate were each associated with significantly improved…