I LIMITI DI CONFIDENZA: UNA RIFLESSIONE SE I RISULTATI NON SONO SIGNIFICATIVI

Use of Confidence Intervals in Interpreting Nonstatistically Significant Results Alexander T. Hawkins, MD, MPH; Lauren R. Samuels, PhD The goal of much of medical research is to determine which of 2 or more therapeutic approaches is most effective in a given situation. The power of a study is the probability of detecting a true treatment…

NUTRIZIONE PER PREVENIRE LA MALATTIA CARDIACA. UNO STATEMENT DALLA AMERICAN HEART ASSOCIATION (free)

2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association Alice H. Lichtenstein et ali. Abstract Poor diet quality is strongly associated with elevated risk of cardiovascular disease morbidity and mortality. This scientific statement emphasizes the importance of dietary patterns beyond individual foods or nutrients, underscores the critical role of…

MA LO SCREENING PER IL CANCRO DEL PANCREAS FUNZIONA? UNA REVIEW DA GASTROENTEROLOGY

Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis Ankit Chhoda et al.  Abstract Background and Aims Identification and resection of successful targets, i.e., T1 N0M0 pancreatic ductal adenocarcinoma (PDAC) and high-grade precursors during surveillance of high-risk individuals (HRIs) confers improved survival. Late-stage PDACs refer to T2-4 N0M0 and nodal or distant metastatic PDAC stages…

MALNUTRIZIONE DURANTE IL RICOVERO IN OSPEDALE: ATTENZIONE ! UNA REVIEW DA LANCET

Management of disease-related malnutrition for patients being treated in hospital Philipp Schuetz et al. Abstract Disease-related malnutrition in adult patients who have been admitted to hospital is a syndrome associated with substantially increased morbidity, disability, short-term and long-term mortality, impaired recovery from illness, and cost of care. There is uncertainty regarding optimal diagnostic criteria, definitions…

DRENAGGIO DELLA COLECISTI PER VIA ECOENDOSCOPICA VERSUS COLECISTOSTOMIA PER VIA PERCUTANEA. UNA META-ANALISI CON LA TECNICA DELLA “SEQUENTIAL ANALYSIS” DAL GRUPPO DELLA EMILIA-ROMAGNA

Trial sequential analysis of EUS-guided gallbladder drainage versus percutaneous cholecystostomy in patients with acute cholecystitis AlessandroCucchetti et al. Abstract Background and Aims Meta-analytic comparison of endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) versus percutaneous gallbladder drainage (PT-GBD) for acute cholecystitis (AC) brings the risk of spurious results if too few studies are included. Trial sequential analysis (TSA)…