CANCRO GASTRICO: UNA OTTIMA REVISIONE 2022 DA “JAMA SURG” (FREE)

Surgical Management of Gastric Cancer: A Review George Z. Li et al. Abstract Importance  Surgery plays a critical role in the management of all stages of gastric cancer. Observations  For patients with early gastric cancer and low risk of lymph node metastasis, endoscopic therapy or surgery alone is potentially curative. Novel techniques, such as sentinel lymph node biopsy,…

DIVERTICOLITE ED EMORRAGIA: RISCHIO DI FANS ED ASPIRINA. UNA OTTIMA META-ANALISI DA UN GRUPPO ITALIANO

Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies Salvatore Longo et al. Abstract Background: The role of non-steroidal anti-inflammatory drugs (NSAIDs) and acetylsalicylic acid in the occurrence of diverticular bleeding (DB), complicated diverticulitis (CD), and acute diverticulitis (AD) is not yet defined. Aim: Update…

RISCHIO DI DIVERTICOLITE: DIETA E MARCATORI DI INFIAMMAZIONE SUGGERISCONO UN SOTTOGRUPPO DI PAZIENTI CHE MERITA LA PREVENZIONE FARMACOLOGICA. DA “CLINICAL GASTRO&HEPATOLOGY”

Association Between Inflammatory Diets, Circulating Markers of Inflammation, and Risk of Diverticulitis Wenjie Ma et al. BACKGROUND & AIMS: Lifestyle and dietary risk factors for diverticulitis also have been associated with chronic inflammation. We performed a prospective study of associations among the inflammatory potential of diets, circulating markers of inflammation, and the incidence of diverticulitis.…

LA DIAGNOSI PRECOCE DEL CANCRO DEL PANCREAS VIA ANALISI DEL MICROBIOMA FECALE: L’EDITORIALE DI “GUT” (FREE)

Finding clues in unexpected places: detection of pancreatic cancer through the faecal microbiome Rachel Newsome AND Christian Jobin Pancreatic cancer is an intractable form of cancer that ranks as the 12th most common cancer worldwide (2.7%) but alarmingly is predicted to increase in the next two decades.1 Pancreatic ductal adenocarcinoma (PDAC) is the most common form…

DIAGNOSI PRECOCE DEL CANCRO DEL PANCREAS: UN MARCATORE FECALE AD ALTA SPECIFICITA’ : AUROC 0.94. DA “GUT” (FREE)

A faecal microbiota signature with high specificity for pancreatic cancer   Ece Karta et al. Abstract Background Recent evidence suggests a role for the microbiome in pancreatic ductal adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and salivary microbiota as potential diagnostic biomarkers. Methods We applied shotgun metagenomic and 16S rRNA amplicon sequencing to samples from…

NASH: UNA REVISIONE SISTEMATICA SULLE ULTIME TERAPIE. DA “LANCET” : PRIMO NOME ALBERTO MANTOVANI (VERONA)

Efficacy of peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors for treatment of non-alcoholic fatty liver disease: a systematic review Alessandro Mantovani  et al. There are no licensed treatments for non-alcoholic fatty liver disease (NAFLD), but three different classes of antihyperglycaemic drugs—peroxisome proliferator-activated receptor (PPAR) agonists, glucagon-like peptide-1 receptor (GLP-1R) agonists,…