Hepatitis D Virus Infection Tarik Asselah and Mario Rizzetto Hepatitis D virus (HDV), also known as hepatitis delta virus, is a defective, hepatotropic pathogenic agent. The life cycle of HDV requires the hepatitis B surface antigen (HBsAg) provided by hepatitis B virus (HBV).1 Like HBV, HDV is transmitted by the parenteral route through infectious body fluids;…
Hemostatic Powder vs Standard Endoscopic Treatment for Gastrointestinal Tumor Bleeding: A Multicenter Randomized Trial Rapat Pittayanon et al. Background & Aims Current guidelines vary as to their recommendations addressing the role of hemostatic powders when managing patients with malignant gastrointestinal (GI) bleeding because these are based on very-low- to low-quality evidence, in large part due to…
The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease Loris Riccardo Lopetuso et al. Abstract Background Several randomised clinical trials (RCTs) performing faecal microbiota transplantation (FMT) for the management of inflammatory bowel disease (IBD), particularly for ulcerative colitis, have recently been published, but with major variations in…
Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept Alessandro Vitale e HCC Special Interest Group of the Italian Association for the Study of the Liver. Summary Advances in the surgical and systemic therapeutic landscape of hepatocellular carcinoma have increased the complexity of patient management. A dynamic adaptation of the available staging-based algorithms…
Yuval Noah Harari argues that artificial intelligence has hacked the operating system of human civilization. Fears of artificial intelligence (AI) have haunted humanity since the dawn of the computer age. Until now these fears have focused on machines using physical means to kill, enslave or replace humans. But in the last two years, new artificial…
Meta-Analysis of Randomized Clinical Trials on Long-Term Outcomes of Surgical Treatment of Perforated Diverticulitis Horesh, Nir et al. Abstract Objective: Assess long-term outcomes of patients with perforated diverticulitis treated with resection or laparoscopic lavage (LL). Summary Background Data: Surgical treatment of perforated diverticulitis changed in the last few decades. LL and increasing evidence that primary anastomosis (PRA) is feasible in certain patients have broadened…