EPATITE DA VIRUS C. UNA GRANDE REVISIONE OTTOBRE 2023 , L’ULTIMA, DA “LANCET”.

Hepatitis C Marianne Martinello, PhD  et al. Summary Hepatitis C virus (HCV) is a hepatotropic RNA virus that can cause acute and chronic hepatitis, with progressive liver damage resulting in cirrhosis, decompensated liver disease, and hepatocellular carcinoma. In 2016, WHO called for the elimination of HCV infection as a public health threat by 2030. Despite…

COLITE ULCEROSA DELL’ADULTO: epidemiologia, fisiopatologia, diagnosi, e terapia. OTTIMA REVIEW DA”JAMA”.

Ulcerative Colitis in Adults A Review Beatriz Gros, MD; Gilaad G. Kaplan, MD, MPH This review focuses on the epidemiology, pathophysiology, diagnosis, and treatment of UC. IMPORTANCE Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, with a prevalence exceeding 400 per 100 000 in North America. Individuals with UC have a lower…

POLIPROTECT ED OMEPRAZOLO SONO EQUIPOTENTI NELLA GESTIONE DELLA MRGE SENZA ESOFAGITE! UN TRIAL ITALIANO DA “AM JOURNAL OF GASTROENTEROLOGY” (FREE)

Poliprotect vs Omeprazole in the Relief of Heartburn, Epigastric Pain, and Burning in Patients Without Erosive Esophagitis and Gastroduodenal Lesions: A Randomized, Controlled Trial Corazziari, Enrico Stefano MD; Gasbarrini, Antonio MD et al  Abstract INTRODUCTION: In the treatment of upper GI endoscopy-negative patients with heartburn and epigastric pain or burning, antacids, antireflux agents, and mucosal…

ATTENZIONE IBDOLOGI! LA RESEZIONE ILEOCECALE PER IL MORBO DI CROHN POTREBBE AVERE UN RUOLO COME PRIMA TERAPIA RISPETTO AGLI ANTI-TNF! LO STUDIO PREDICT SU POPOLAZIONE DA “GASTROENTEROLOGY” (FREE).

Early Ileocecal Resection for Crohn’s Disease Is Associated With Improved Long-term Outcomes Compared With Anti-Tumor Necrosis Factor Therapy: A Population-Based Cohort Study Manasi Agrawal et al. Background & Aims Early Crohn’s disease (CD) treatment involves anti-tumor necrosis factor (TNF) agents, whereas ileocecal resection (ICR) is reserved for complicated CD or treatment failure. We compared long-term…

PER GLI EPATOLOGI E GLI INTERNISTI! QUALE DOSE DELLA SEMAGLUTIDE ORALE PER IL DIABETE ? UN EDITORIALE DA “LANCET” DI COMMENTO SU DUE TRIAL (FREE).

The pursuit of optimal semaglutide dosing in type 2 diabetes continues Christina H Sherrill , Andrew Y Hwang Diabetes remains a pressing global health concern, affecting approximately 540 million people worldwide.1 As prevalence continues to rise, diabetes places substantial burdens on individuals and health-care systems, influencing overall quality of life and health-care expenditures. Moreover, type 2…

PROBIOTICI E COLON IRRITABILE. ULTIMISSIMA META-ANALISI DA “GASTROENTEROLOGY” (FREE). PECCATO CHE NON SI DISTINGUA TRA FORME STIPSI E DIARREA!

Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis Vivek C. Goodoory et al. BACKGROUND & AIMS: Some probiotics may be beneficial in irritable bowel syndrome (IBS), but differences in species and strains used, as well as endpoints reported, have hampered attempts to make specific recommendations as to which should be preferred. We…