Relative risk rather than absolute risk reduction should be preferred to sensitise the public to preventive actions: letter Nicolas Chapelle et al. We thank Lawrence and colleagues1 for their interest in our work,2 about which they raised some comments as the need of expressing results in absolute rather than relative risks. As they appropriately mentioned in…
L’elogio dell’incertezza: una revisione sistematica living per valutare l’efficacia e la sicurezza dei trattamenti farmacologici per pazienti affetti da covid-19 FABIO CRUCIANI et al. Riassunto. Introduzione. Il SARS-CoV-2 è un coronavirus che causa una malattia che può evolvere in una polmonite interstiziale potenzialmente letale. A dicembre 2020 in Italia più di 2 milioni di persone hanno…
Meta-analysis of the Parkinson’s disease gut microbiome suggests alterations linked to intestinal inflammation Stefano Romano et al. Abstract The gut microbiota is emerging as an important modulator of neurodegenerative diseases, and accumulating evidence has linked gut microbes to Parkinson’s disease (PD) symptomatology and pathophysiology. PD is often preceded by gastrointestinal symptoms and alterations of the…
How to interpret p-value with COVID-19 data [No more confusion] How to find a p-value and ultimately reject the null hypothesis Aerin Kim f you read any scientific papers, e.g. medical, artificial intelligence, climate, political, etc., or any poll result, there is a term that almost always appears — the p-value. But what exactly is…
Management of colonic diverticulitis Anne F Peery ABSTRACT Left sided colonic diverticulitis is a common and costly gastrointestinal disease in Western countries, characterized by acute onset of often severe abdominal pain. Imaging is necessary to make an initial diagnosis and determine disease severity. Colonoscopy should be done six to eight weeks after diagnosis to…
Proton pump inhibitor on susceptibility to COVID-19 and its severity: a systematic review and meta-analysis Raymond Pranata et al. Abstract Background: The negative impacts of proton pump inhibitor (PPI), including the risk of pneumonia and mortality, have been reported previously. This meta-analysis aimed to address the current interest of whether the administration of PPI could increase…