Proton pump inhibitor usage reduces sustained viral response rates for veterans with HIV/HCV coinfection on ledipasvir/sofosbuvir: a real‐world study from a multicentre VA cohort Tzu‐Hao Lee et al. Abstract Previous studies have reported an association of proton pump inhibitor (PPI) use and decreased sustained viral response rate (SVR) in patients taking ledipasvir/sofosbuvir (LDV/SOF). The relationship…
SARS-CoV-2 Vaccines C. Buddy Creech, MD, MPH; Shannon C. Walker, MD; Robert J. Samuels, MBChB Shortly after SARS-CoV emerged at the turn of the 21st century, the spike (S) protein (particularly in its prefusion [native] conformation) was identified as the immunodominant antigen of the virus.1 Evaluation of patients with SARS-CoV-2 revealed that binding and neutralizing…
Long-term dietary patterns are associated with proinflammatory and anti-inflammatory features of the gut microbiome Laura A Bolte et al. Abstract Objective The microbiome directly affects the balance of pro-inflammatory and anti-inflammatory responses in the gut. As microbes thrive on dietary substrates, the question arises whether we can nourish an anti-inflammatory gut ecosystem. We aim to unravel interactions…
MHRA issues new advice, concluding a possible link between COVID-19 Vaccine AstraZeneca and extremely rare, unlikely to occur blood clots The benefits of vaccination continue to outweigh any risks but the MHRA advises careful consideration be given to people who are at higher risk of specific types of blood clots because of…
REVIEW ARTICLE Gastritis: The clinico-pathological spectrum Massimo Rugge et al. Summary The inflammatory spectrum of gastric diseases includes different clinico-pathological entities, the etiology of which was recently established in the international Kyoto classification. A diagnosis of gastritis combines the information resulting form the gross examination (endoscopy) and histology (microscopy). It is important to consider the…
CDC Real-World Study Confirms Protective Benefits of mRNA COVID-19 Vaccines Study involved health care personnel, first responders, and essential workers in six states Press Release Embargoed until: 11 a.m. ET, Monday, March 29, 2021 Contact: Media Relations (404) 639-3286 A new CDC study provides strong evidence that mRNA COVID-19 vaccines are highly effective in preventing SARS-CoV-2…