Endoscopic ultrasound-guided therapies for pancreatic solid tumors: An overview Alberto LarghI et al. ABSTRACT The close proximity of the endoscopic ultrasound (EUS) probe to the pancreas, coupled with the ease with which a needle can be inserted into a pancreatic lesion, have contributed to the development of EUS-guided therapies for both adenocarcinoma and neuroendocrine pancreatic neoplasms.…
Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: a systematic review Hayley Fowler et al. Abstract Background: The aim of this study was to assess failure rates following nonoperative management of acute diverticulitis complicated by abscess and trends thereof. Method: Pubmed, MEDLINE, EMBASE, CINAHL, Cochrane Library, and Web of Science were systematically searched.…
The Automatic Substitution of Biosimilars: Definitions of Interchangeability are not Interchangeable Anita Afzali et al. Abstract In the USA, an interchangeability designation provides biosimilar sponsors with a pathway for achieving what is standard for small-molecule generics: pharmacy-level auto-substitution for an innovator. No other major health authority links interchangeability to automatic substitution, as all require the…
How do you treat coronavirus? Here are physicians’ best strategies By Kelly Servick, Jennifer Couzin-Frankel, Catherine MatacicMar. 16, 2021 , 4:37 PM Science’s COVID-19 reporting is supported by the Heising-Simons Foundation. Ready or not, the patients were coming. This time last year, physicians around the world prepared, most for the first time in their careers, to treat a…
Vascular Liver Disorders, Portal Vein Thrombosis, and Procedural Bleeding in Patients With Liver Disease: 2020 Practice Guidance by the American Association for the Study of Liver Diseases Patrick G. Northup et al. New Features and Changes From the Previous American Association for the Study of Liver Diseases Guidelines An overview of the current understanding of…
Gut Microbiota in Patients With Irritable Bowel Syndrome—A Systematic Review Rapat Pittayanon,et al. Background & Aims Irritable bowel syndrome (IBS) is common but difficult to treat. Altering the gut microbiota has been proposed as a strategy for treatment of IBS, but the association between the gut microbiome and IBS symptoms has not been well…