DALLA EBM ALLA EBM + . E’ TEMPO DI UNA NUOVA EBM ! TRISHA GREENHALG COLPISCE ANCORA DA “BMJ EVIDENCE BASED MEDICINE” (FREE).

Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent Trisha Greenhalg et al. Abstract Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to the science of COVID-19. But these methods and tools were designed primarily to…

VERSO UNA DISSEMINAZIONE DELLE EVIDENZE PIU’ RESPONSABILE. DA “BMJ EVIDENCE BASED MEDICINE” (FREE). IL PROBLEMA DEI PRESS RELASE.

Responsible dissemination of health and medical research: some guidance points Raffaella Ravinetto and Jerome Amir Singh Ravinetto and Singh argue that better practices can be implemented when disseminating research findings through abstracts, preprints, peer-reviewed publications, press releases and social media Dissemination has been defined as ‘the targeted distribution of information and intervention materials to a…

ALDACTONE CONTRO LA MALATTIA DA ABUSO DI ALCOL. UN NUOVO APPROCCIO ? INTERESSANTE. DA SEGUIRE!

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies Mehdi Farokhnia et al. Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR) antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may represent a novel pharmacotherapy for alcohol use disorder (AUD). In this study, we tested the effects…

DA DDW 2022. RIFAXIMINA: POOLED ANALYSIS DI 2 TRIAL NELLA IBS-D.

Rifaximin Effective for Multiple Symptoms in Irritable Bowel Syndrome With Diarrhea Colby Stong A 2-week course of rifaximin significantly improved multiple abdominal symptoms in patients with irritable bowel syndrome with diarrhea (IBS-D), according to study results presented at Digestive Disease Week (DDW), held from May 21 to 24, 2022, in San Diego, California, and virtually.…

PREVENZIONE DELLE INFEZIONI NEL CIRROTICO. UNA GRANDE REVIEW OPEN. DA “Semin Liver Dis” (FREE !). GUARDATE PER CREDERE!

Early Diagnosis and Prevention of Infections in Cirrhosis Anand V. Kulkarn et al. Abstract Strategies to prevent infection and improve outcomes in patients with cirrhosis. HAV, hepatitis A virus; HBV, hepatitis B virus; COVID-19, novel coronavirus disease 2019; NSBB, nonselective β-blocker; PPI, proton pump inhibitors. Cirrhosis is a risk factor for infections. Majority of hospital…