COLITE ULCEROSA ACUTA SEVERA: RUOLO DEGLI JAK INHIBITORS. UN’OTTIMA META-ANALISI! DA “CLINICAL GASTROENTEROLOGY & HEPATOLOGY”

CHIRURGIA, GASTROENTEROLOGIA, IBD, NEWSLETTER

Effectiveness and safety of JAK inhibitors in acute severe ulcerative colitis: A systematic review and meta-analysis lAnuraag Jena  et al. Abstract Background & aims Janus kinase (JAK) inhibitors have been reported to be useful in acute severe ulcerative colitis (ASUC). We performed a systematic review and meta-analysis to assess their effectiveness and safety in ASUC. Methods…

COLANGITE SCLEROSANTE PRIMITIVA: UNA RAPIDA REVIEW DA 2 MINUTI! DA “J OF CLINICAL MEDICINE”

DIAGNOSTICA PER IMMAGINI, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, MEDICINA INTERNA, NEWSLETTER

Primary Sclerosing Cholangitis: Diagnosis, Management, and Clinical Challenges Sofia Svensson Di Giorgio et al Abstract Primary sclerosing cholangitis is a rare, chronic, inflammatory disease of the biliary tree that leads to progressive ductal obliteration, hepatic dysfunction, and ultimately liver cirrhosis. Most patients eventually require liver transplantation or develop serious complications, the most severe being end-stage…

COLITE ULCEROSA: LA APPENDICECTOMIA MIGLIORA LA RISPOSTA CLINICA NEI PAZIENTI REFRATTARI ALLA TERAPIA CON BIOLOGICI RISPETTO AI JAK INHIBITORS. UN TRIAL IMPORTANTE! DA”THE LANCET GASTRO&HEPAT”

CHIRURGIA, GASTROENTEROLOGIA, IBD, NEWSLETTER

Appendicectomy versus switching to a JAK inhibitor in inducing remission in patients with active ulcerative colitis after biologic therapy failure (COSTA): 1-year results of a multicentre, prospective, cohort study Eva Visser et al. Summary Background Although retrospective and limited prospective observational studies have suggested a potential benefit of appendicectomy in therapy-refractory ulcerative colitis, its effectiveness…

ESOFAGO DI BARRETT: LE ULTIME LINEE GUIDA DELL’AGA. OCCHIO AL p53 . ED AL CAMPIONAMENTO PRAGA VS SEATTLE. ED ALLA CLASSIFICAZIONE DI SEATTLE. DA”GASTROENTEROLOGY” (FREE)

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AGA Clinical Practice Guideline on Surveillance of Barrett’s Esophagus Sachin Wani et al. Abstract Background & Aims Barrett’s esophagus (BE) is the only identifiable precursor to esophageal adenocarcinoma (EAC). Endoscopic surveillance has been proposed for early detection of BE-related neoplasia and reducing EAC mortality. This clinical practice guideline aims to inform clinicians and patients by providing…

DISPEPSIA FUNZIONALE. UNA REVIEW DA TALLEY 2026. AVETE 3 MINUTI? GRANDE! DA “NEJM” (FREE)

DISPEPSIA, GASTROENTEROLOGIA, IBS, MEDICI DI FAMIGLIA, MEDICINA DEI PROBIOTICI, MEDICINA INTERNA, NEWSLETTER, NUTRIZIONE

Functional Dyspepsia Pankaj J. Pasricha and Nicholas J. Talley  Summary Functional dyspepsia is a common but serious medical syndrome that can induce weight loss and food aversion and may be associated with increased risks of hospitalization and death. It probably comprises several different and as yet incompletely characterized disorders. Patients with local mucosal microinflammation driven by…

A PROPOSITO DI DIARREA: MEGLIO DARE UN’OCCHIATA ALL’ULTIMA REVIEW SULLA DIARREA CRONICA! ASCOLTATECI! DA”JAMA” (FREE)

GASTROENTEROLOGIA, IBD, IBS, MEDICI DI FAMIGLIA, MEDICINA DEI PROBIOTICI, MEDICINA INTERNA, NEWSLETTER

Chronic, Noninfectious DiarrheaA Review Prashant Singh et al. Abstract Importance  Chronic diarrhea is defined as loose or watery stools lasting longer than 4 weeks and affects approximately 6% to 7% of adults in the US. More than 90% of patients with chronic diarrhea have a noninfectious etiology. Observations  The most common causes of chronic, noninfectious diarrhea are…