TENOFOVIR MEGLIO DI ENTECAVIR PER PREVENIRE HCC IN EPATITE CRONICA DA VIRUS B? UN’OTTIMA META-ANALISI

Comparative Effectiveness of Entecavir Versus Tenofovir for Preventing Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: A Systematic Review and Meta‐Analysis Shravan Dave et al. Abstract Background and Aims Chronic hepatitis B (CHB) can lead to hepatocellular carcinoma (HCC). While both tenofovir disoproxil (TDF) and entecavir (ETV) have been shown to reduce the risk of…

COLITE MICROSCOPICA: LINEE GUIDA EUROPEE 2021

European guidelines on microscopic colitis: United European Gastroenterology and European Microscopic Colitis Group statements and recommendations Stephan Miehlke et al. INTRODUCTION: Microscopic colitis is a chronic inflammatory bowel disease characterised by normal or almost normal endoscopic appearance of the colon, chronic watery, nonbloody diarrhoea and distinct histological abnormalities, which identify three histological subtypes, the collagenous colitis,…

AGGIUNGI TERAPIA ANTICOAGULANTE AL PAZIENTE CON COVID 19 PER PREVENIRE LA MORTALITA’. STUDIO OSSERVAZ. USA SU 4300 PAZIENTI

Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study Christopher T Rentsch et al. Abstract Objective To evaluate whether early initiation of prophylactic anticoagulation compared with no anticoagulation was associated with decreased risk of death among patients admitted to hospital with…

TERLIPRESSINA FA REGREDIRE LA SINDROME EPATORENALE DI TIPO 1 NEL 40% DEI CASI

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome Florence Wong, et al. Abstract BACKGROUND The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome (HRS-1) in many parts of the world and is part of the clinical practice guidelines in Europe. METHODS We conducted a phase 3 trial to confirm the efficacy…

COLON IRRITABILE. UNA REVIEW DA CAMILLERI

Diagnosis and Treatment of Irritable Bowel Syndrome. A Review Michael Camilleri, MD Abstract Importance  The prevalence of irritable bowel syndrome (IBS) in the United States is between 7% and 16%, most common in women and young people, with annual direct costs estimated at more than $1 billion dollars in the United States. Traditionally, the diagnosis of…

UNO SCORE DI FACILE USO PER IDENTIFICARE IL PAZIENTE CON CIRROSI NEL TUO STUDIO

Can routine blood tests be modelled to detect advanced liver disease in the community: model derivation and validation using UK primary and secondary care data  Theresa Hydes et al. Abstract Objectives Most patients are unaware they have liver cirrhosis until they present with a decompensating event. We therefore aimed to develop and validate an algorithm to…