I DUE NUOVI ANTIVIRALI PER IL COVID-19: MOLNUPIRAVIR E NIRMATRELVIR/RITONAVIR . DAL “DRUG AND THERAPEUTIC BULLETTIN (BMJ)”(FREE)

COVID19 - EVIDENCE, MEDICI DI FAMIGLIA, MEDICINA INTERNA

Two new oral antivirals for covid-19: ▼molnupiravir and ▼nirmatrelvir plus ritonavir   Abstract This article is made freely available for personal use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial…

COCHRANE REVIEWS: LA MAGGIOR PARTE DEGLI INTERVENTI SANITARI SEGNALATI NON SONO EFFICACI SE VALUTATI PER EVIDENZA DI ELEVATA QUALITA’. IL GRUPPO DI JOANNIDIS COLPISCE ANCORA

EVIDENCE CORNER, GLOBAL HEALTH, METODOLOGIA, REAL WORLD EVIDENCE, Senza categoria

Most healthcare interventions tested in Cochrane Reviews are not effective according to high quality evidence: a systematic review and meta-analysis JeremyHowick et al. Highlights • In this large sample of 1567 interventions studied within Cochrane reviews, effects of most interventions (94%) interventions were not supported by high quality evidence. • Potential harms of healthcare interventions…

ENCEFALOPATIA GRADO 3-4: METABOLITI DI ORIGINE BATTERICA, E BASSI LIVELLI DI ISOLEUCINA, TIROSINA E LISOFOSFOLIPIDI SONO PREDITTIVI DI BRAIN FAILURE.

CIRROSI EPATICA, ENCEFALOPATIA, EPATOLOGIA, GASTROENTEROLOGIA, Senza categoria

Admission Serum Metabolites and Thyroxine Predict Advanced Hepatic Encephalopathy in a Multi-center Inpatient Cirrhosis Cohort Jasmohan S Bajaj et al. Abstract: Background and Aims Grade 3-4 hepatic encephalopathy (advanced HE), also termed brain failure (BF), is an organ failure that defines acute-on chronic liver failure. It is associated with poor outcomes in cirrhosis but cannot…

EPATOCARCINOMA DA EPATITE CRONICA DA VIRUS B. ENTECAVIR vs TENOFOVIR. UNA COORTE NAZIONALE DALLA COREA. “JAMA ONCOLOGY” (FREE)

EPATOLOGIA, EPATOLOGIA ONCOLOGICA, REAL WORLD EVIDENCE, Senza categoria

Risk of Hepatocellular Carcinoma in Patients Treated With Entecavir vs Tenofovir for Chronic Hepatitis B A Korean Nationwide Cohort Study Jonggi Choi, M et al. IMPORTANCE Entecavir and tenofovir disoproxil fumarate have comparable efficacy in achieving surrogate end points, including virologic response, and are equally recommended as first-line treatments for patients with chronic hepatitis B…

INSUFFICIENZA ACUTA EPATICA SU CRONICO: L’ULTIMA LINEA GUIDA DAL GRUPPO DI BAJAJ. “AMERICAN J. OF GASTROENTEROLOGY” 2022 (FREE)

EPATOLOGIA, GASTROENTEROLOGIA, LINEE GUIDA EBM, Senza categoria

Acute-on-Chronic Liver Failure Clinical Guidelines Jasmohan S. Bajaj et al. In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging as a major cause of mortality. These guidelines indicate the preferred approach to the management of patients with acute-on-chronic liver failure and represent the official practice recommendations of the American College of…

COLON IRRITABILE E DIETA: UNA EXPERT REVIEW DALLA AMERICAN GASTROENTEROLOGICAL ASSOCIATION. “GASTROENTEROLOGY” (FREE).

GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NUTRIZIONE

AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review William D. Chey DESCRIPTION: Irritable bowel syndrome (IBS) is a commonly diagnosed gastrointestinal disorder that can have a substantial impact on quality of life. Most patients with IBS associate their gastrointestinal symptoms with eating food. Mounting evidence supports dietary modifications,…