PROBABILITA’ PRE-TEST: MINIMA O MASSIMA PER TE NON PARI SONO PER DECIDERE! DA “JOURNAL OF CLINICAL EPIDEMIOLOGY”

METODOLOGIA

Use of minimum and maximum pretest probabilities to conclude with confidence after obtaining a diagnostic test result Loic Desquilbet et al.  Highlights • Predictive values guide decisions only if based on pretest probability. • Predictive values do not depend only on disease prevalence in clinical medicine. • Clinicians must estimate pretest probability from the full clinical…

DRENAGGIO DELLA COLECISTI VIA ECOENDOSCOPIA: LA CONSENSUS ITALIANA TRA SPECIALISTI SU 22 RACCOMANDAZIONI. OCCHIO ECOENDOSCOPISTI GASTROENTEROLOGI! DA “ENDOSCOPIC ULTRASOUND” (FREE!)

ECOGRAFIA ED ECOENDOSCOPIA, METODOLOGIA, NEWSLETTER

The i-EUS consensus on EUS-guided gallbladder drainage: A 3-step modified Delphi approach Facciorusso, Antonio et al. per  [i-EUS Working Group] Abstract Background and Objective EUS-guided gallbladder drainage (EUS-GBD) has emerged as a viable alternative for patients with acute cholecystitis who are unfit for surgery. However, standardized guidelines for its indications, techniques, and management remain limited.…

NEOPLASIA VIE BILIARI DISTALI: MEGLIO LA PROTESI VIA COLEDOCODUODENOSTOMIA SOTTO GUIDA ECOENDO O VIA CPRE PER PREVENIRE LA PANCREATITE? VINCE LA COLEDOCODUODENOSTOMIA ! UN GRANDE TRIAL MULTICENTRICO ITALIANO DA “GASTROENTEROLOGY”

ECOGRAFIA ED ECOENDOSCOPIA, ENDOSCOPIA, EPATOLOGIA ONCOLOGICA, NEWSLETTER, ONCOLOGIA, PANCREAS E VIE BILIARI

Endoscopic Ultrasound-Guided Choledochoduodenostomy vs Endoscopic Retrograde Cholangiopancreatography in Malignant Distal Biliary Obstruction to Prevent Postprocedural Pancreatitis: A Randomized Trial Andrea Anderloni et al. Abstract Background & Aims Postprocedural pancreatitis is the most common adverse event (AE) associated with endoscopic retrograde cholangiopancreatography (ERCP). Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) using a lumen-apposing metal stent is emerging as a promising…

CANCRO PANCREAS. LO STATO NUTRIZIONALE DI BASE PREDICE LA RISPOSTA ALLA CHEMIOTERAPIA E LA SOPRAVVIVENZA.UN OTTIMO STUDIO PROSPETTIVO DI COORTE. DA “CLINICAL NUTRITION”

CHIRURGIA, GASTROENTEROLOGIA, NEWSLETTER, NUTRIZIONE, ONCOLOGIA, PANCREAS E VIE BILIARI

Impact of nutritional status on chemotherapy delivery and outcomes in advanced pancreatic cancer: A prospective multicenter study Maria Kiriukova, Gabriele Capurso et al. Summary Background & aim Malnutrition is common in pancreatic ductal adenocarcinoma (PDAC) and may compromise chemotherapy delivery. We investigated whether baseline nutritional status and quality of life (QoL) predict chemotherapy relative dose intensity…

MORBO DI CROHN: INIBITORI DELLA IL-23p19 vs IL-12/23p40. UNA MAGNIFICA REVISIONE SISTEMATICA CON NETWORK META-ANALISI. DA “ANNALS OF MEDICINE” (FREE!)

GASTROENTEROLOGIA, IBD, NEWSLETTER

Efficacy and safety of IL-23p19 and IL-12/23p40 inhibitors in moderate-to-severe Crohn’s disease: a systematic review and network meta-analysis Motoki Kaneko, Atsushi Sakuraba  Abstract Background Interleukin (IL)-23 inhibitors—including IL-23p19 inhibitors (guselkumab, mirikizumab, risankizumab) and the IL-12/23p40 inhibitor ustekinumab—are emerging treatments for Crohn’s disease (CD), but comparative data among them remain limited. Most previous network meta-analyses (NMAs) compared IL-23…

SENSIBILITA’ AL GLUTINE NON-CELIACA. UNA GRANDE REVISIONE DI CAROLINA CIACCI E COLLEGHI. DA “THE LANCET”

GASTROENTEROLOGIA, IBS, MEDICI DI FAMIGLIA, MEDICINA DEI PROBIOTICI, NEWSLETTER, NUTRIZIONE

Non-coeliac gluten sensitivity Jessica R Biesiekierski, Carolina Ciacci, MDcet al. Non-coeliac gluten sensitivity (NCGS) refers to individuals who report intestinal and extraintestinal symptoms related to the ingestion of gluten-based or wheat-based foods, in the absence of coeliac disease or wheat allergy. Gluten is found in multiple cereals, including wheat, rye, and barley, although the precise trigger of…