COVID-19 ED INCERTEZZA: ASPIRINA SI’!

COVID19 - EVIDENCE, MEDICI DI FAMIGLIA, MEDICINA INTERNA, METODOLOGIA, Senza categoria

Association of mortality and aspirin prescription for COVID-19 patients at the Veterans Health Administration Thomas F. Osborne et al. Abstract There is growing evidence that thrombotic and inflammatory pathways contribute to the severity of COVID-19. Common medications such as aspirin, that mitigate these pathways, may decrease COVID-19 mortality. This retrospective assessment was designed to quantify…

L’INCIDENZA DELLA PANCREATITE E’ IN FORTE AUMENTO: UNA REVISIONE SISTEMATICA ED UNA META-ANALISI DA GASTROENTEROLOGY

CHIRURGIA, GASTROENTEROLOGIA, GLOBAL HEALTH, PANCREAS E VIE BILIARI, REAL WORLD EVIDENCE, Senza categoria

Global Incidence of Acute Pancreatitis Is Increasing Over Time: A Systematic Review and Meta-Analysis Jordan P. Iannuzzi et al. Background & Aims Acute pancreatitis is a common disease with significant associated morbidity and mortality. We performed a systematic review and meta-analysis of population-based studies to explore the changing temporal trends of acute pancreatitis incidence globally.…

ESCE IL TRIAL CON IL MOLNUPIRAVIR PER OS COME ANTICOVID-19: DAL NEW ENGLAND JOURNAL OF MEDICINE DEL 16 DICEMBRE (FREE) (-50% DI RICOVERI)

COVID19 - EVIDENCE, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, Senza categoria

Molnupiravir for Oral Treatment of Covid-19 in Nonhospitalized Patients Angélica Jayk Bernal et al. BACKGROUND New treatments are needed to reduce the risk of progression of coronavirus disease 2019 (Covid-19). Molnupiravir is an oral, small-molecule antiviral prodrug that is active against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). METHODS We conducted a phase 3, double-blind,…

LA NUOVA VIA ALLA DIAGNOSI. LEGGETE! LA INTELLIGENZA ARTIFICIALE CAMBIA IL PARADIGMA ? DA JAMA (FREE)

METODOLOGIA, REAL WORLD EVIDENCE, Senza categoria

Next-Generation Artificial Intelligence for Diagnosis From Predicting Diagnostic Labels to “Wayfinding” Julia Adler-Milstein et al. Improving the diagnostic process is a quality and safety priority.1 With the digitization of health records and rapid expansion of health data, the cognitive demand on the diagnostician has increased. The use of artificial intelligence (AI) to assist human cognition has…

USTEKINUMAB VS VEDOLIZUMAB NEL CROHN REFRATTARIO AL TNF. UNA OTTIMA META-ANALISI

GASTROENTEROLOGIA, IBD, Senza categoria

Systematic review with meta-analysis: the effectiveness of either ustekinumab or vedolizumab in patients with Crohn’s disease refractory to anti-tumour necrosis factor Laurène Parrot, et al. Summary Background Ustekinumab and vedolizumab are commonly used after anti-tumour necrosis factor (TNF) failure in patients with Crohn’s disease (CD). No randomised controlled trial has compared these drugs. Aims To…

BAND LIGATION E’ SUPERIORE AL CLIPPING NELLA EMORRAGIA DA DIVERTICOLI. UN GRANDE STUDIO OSSERVAZIONALE GIAPPONESE SU ENDOSCOPY

ENDOSCOPIA, GASTROENTEROLOGIA, MALATTIA DIVERTICOLARE, Senza categoria

Effectiveness and adverse events of endoscopic clipping versus band ligation for colonic diverticular hemorrhage: A large-scale multicenter cohort study Katsumasa Kobayashi et al. Abstract Background and study aims: Prior studies have shown the effectiveness of endoscopic band ligation (EBL) and clipping for colonic diverticular hemorrhage (CDH) but have been small and conducted at single centers. Thus,…