LA CLASSIFICAZIONE ENDOSCOPICA “DICA” HA UN RUOLO RILEVANTE NEL PREDIRE LA DIVERTICOLITE! UN GRANDE STUDIO PROSPETTICO ITALIANO SU GUT

Prognostic performance of the ‘DICA’ endoscopic classification and the ‘CODA’ score in predicting clinical outcomes of diverticular disease: an international, multicentre, prospective cohort study. Antonio Tursi et al. Abstract Objective To investigate the predictive value of the Diverticular Inflammation and Complication Assessment (DICA) classification and to develop and validate a combined endoscopic-clinical score predicting clinical outcomes…

MA COS’E’ ‘STA “TRIAL SEQUENTIAL ANALYSIS” ? UNA OTTIMA SEMPLICE INTRODUZIONE DA RICERCATORI ITALIANI SU UN NUOVO PARADIGMA (FREE)

Trial sequential analysis: plain and simple Alessandro De Cassai et al. The use of trial sequential analysis (TSA) in the medical literature is increasing in recent times. However, not all readers may be familiar with this statistical technique. This correspondence aims to provide readers with the essentials to understand and interpret TSA. Adequately conducted meta-analyses…

DIVERTICOLITE: UNA GUIDA PRATICA DALLA AGA. UNA REVISIONE TRA ESPERTI 2021

AGA Clinical Practice Update on Medical Management of Colonic Diverticulitis: Expert Review Anne F Peery et al. Abstract Colonic diverticulitis is a painful gastrointestinal disease that recurs unpredictably and can lead to chronic gastrointestinal symptoms. Gastroenterologists commonly care for patients with this disease. The purpose of this Clinical Practice Update is to provide practical and…

PERCHE’ E’NECESSARIO CONFRONTARE IL TASSO DI DECESSI TRA VACCINATI E NON-VACCINATI: UNA RIFLESSIONE PER GLI AMICI NO-VAX DA “OUR WORLD IN DATA” (FREE)

Why we need to compare the rates of death between vaccinated and unvaccinated During a pandemic, you might see headlines like “Half of those who died from the virus were vaccinated”. It would be wrong to draw any conclusions about whether the vaccines are protecting people from the virus based on this headline. The headline is not…

I NUOVI AGENTI ANTIVIRALI PER IL COVID-19: UNA OTTIMA RIFLESSIONE DA “NATURE REVIEWS” (FREE)

A tale of two antiviral targets — and the COVID-19 drugs that bind them The FDA is considering authorizations for Pfizer’s paxlovid and Merck & Co.’s molnupiravir, the first two oral COVID-19 antivirals. Megan Cully COVID-19, for all of the problems it has created, has shown the unprecedented speed with which drug developers can move.…