Ancora news sull’interazione tra PPI e clopidogrel…
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised…
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Clopidogrel : forse non è necessario evitare l’associazione con PPI
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised…
Lo stile di vita è determinnante nella prevenzione del danno cardiovascolare
Relation between modifiable lifestyle factors and lifetime risk of heart failure.Djoussé L, Driver JA, Gaziano JM. JAMA. 2009 Jul 22;302(4):394-400.…
Statine nei soggetti con fattori di rischio per patologia cardiovascolare : una meta-analisi
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials.Brugts…
Viaggi e rischio di TVP : una review
Travel and Risk for Venous Thromboembolism.Chandra D, Parisini E, Mozaffarian D. Ann Intern Med. 2009 Jul 6. [Epub ahead of…
Review sistematica sull’uso del cortisone nello shock settico
Corticosteroids in the treatment of severe sepsis and septic shock in adults: a systematic review.Annane D, Bellissant E, Bollaert PE,…
Meta-analisi sugli anti-ipertensivi nella prevenzione del danno cardiovascolare
Use of blood pressure lowering drugs in the prevention of cardiovascular disease: meta-analysis of 147 randomised trials in the context…
Meta-analisi sull’utilizzo dell’aspirina nella prevenzione primaria e secondaria del danno vascolare
Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials.Antithrombotic Trialists’…
Ruolo dell’aldosterone nella sindrome metabolica e nell’ipertensione resistente
Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension.Sowers JR, Whaley-Connell…
PPI e rischio di polmonite : nuove conferme
Acid-Suppressive Medication Use and the Risk for Hospital-Acquired PneumoniaShoshana J. Herzig, Michael D. Howell, Long H. Ngo, Edward R. Marcantonio.JAMA.…
Microalbuminuria e rischio di tromboembolismo
Microalbuminuria and Risk of Venous ThromboembolismBakhtawar K. Mahmoodi; Ron T. Gansevoort; Nic J. G. M. Veeger; Abigail G. Matthews; Gerjan…
Poco efficaci i PPI nei pazienti con asma
Efficacy of esomeprazole for treatment of poorly controlled asthma. American Lung Association Asthma Clinical Research Centers, Mastronarde JG, Anthonisen NR,…
PPI+ clopidogrel: il pantoprazolo non interferisce
A population-based study of the drug interaction between proton pump inhibitors and clopidogrel.Juurlink DN, Gomes T, Ko DT, Szmitko PE,…
Non bisogna associare i PPI al clopidogrel
Risk of adverse outcomes associated with concomitant use of clopidogrel and proton pump inhibitors following acute coronary syndrome. Ho PM,…
Inappropriato uso di PPI e rischio di infezione da C.difficile
Proton Pump Inhibitors (PPI) significantly increase the risk of Clostridium difficile infection in a Low Endemicity, Non-outbreak Hospital Setting: optimizing…
Efficacia di 12 nuovi antidepressivi: una meta-analisi
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis.Cipriani A, Furukawa TA, Salanti G, Geddes JR, Higgins JP,…
Tiazolidone e rischio fratture
Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis.Loke YK, Singh S, Furberg CD. CMAJ. 2009 Jan…
Mortalità e morbidità aumentate in pazienti con scompenso cardiaco che utilizzano FANS
Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure.Gislason GH, Rasmussen JN, Abildstrom…
Meta-analisi sull’efficacia dei generici
Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis.Kesselheim AS, Misono AS, Lee…
Trasfusioni, trombosi e mortalità nei pazienti neoplastici
Blood transfusions, thrombosis, and mortality in hospitalized patients with cancer.Khorana AA, Francis CW, Blumberg N, Culakova E, Refaai MA, Lyman…
Rofecoxib : eventi cardiovascolari in eccesso dopo 1 anno dalla sospensione
Cardiovascular events associated with rofecoxib: final analysis of the APPROVe trial.Baron JA, Sandler RS, Bresalier RS, Lanas A, Morton DG,…
Le statine riducono la mortalità in pazienti con polmonite
Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients.Thomsen RW, Riis A, Kornum…
Survey US sulla prescrizione del placebo
Prescribing “placebo treatments”: results of national survey of US internists and rheumatologists.Tilburt JC, Emanuel EJ, Kaptchuk TJ, Curlin FA, Miller…
Livelli di bilirubina e rischio di ictus
Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004.Perlstein TS, Pande RL, Creager MA, Weuve J, Beckman JA.…
