US drug agency approves potent painkiller — the first non-opioid in decades The FDA’s nod for suzetrigine bolsters confidence in…
Mapping the effectiveness and risks of GLP-1 receptor agonists Yan Xie et al. Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are…
A Clinical Update on MASLD Grace Y. Zhang, MD; Danielle Brandman, MD, MAS Metabolic dysfunction–associated steatotic liver disease (MASLD; formerly…
Antibiotic treatment versus appendicectomy for acute appendicitis in adults: an individual patient data meta-analysis Jochem C G Scheijmans et al. Summary…
Guidelines International Network: Principles for Use of Artificial Intelligence in the Health Guideline Enterprise Bernardo Sousa-Pinto et al. Abstract Description:…
AGA Clinical Practice Update on Management of Portal Vein Thrombosis in Patients With Cirrhosis: Expert Review Jessica P.E. Davis et al.…
Surveillance for Hepatocellular Carcinoma in Cirrhosis: End of Monopoly for Serum Alpha Fetoprotein Lung-Yi Mak ∙ Man-Fung Yuen Hepatocellular carcinoma (HCC) is the final…
A Phase 3 Biomarker Validation of GALAD for the Detection of Hepatocellular Carcinoma in Cirrhosis Tracey L. Marsh et al Abstract…
‘Publish or perish’ culture blamed for reproducibility crisis Survey of more than 1,600 biomedical researchers also flagged small sample sizes…
Thermal ablation versus surgical resection of small-size colorectal liver metastases (COLLISION): an international, randomised, controlled, phase 3 non-inferiority trial Susan…
Placebo Rates in Crohn’s Disease Randomized Clinical Trials: An Individual Patient Data Meta-Analysis Virginia Solitano et al. Abstract Background & Aims…
AGA Clinical Practice Update on Endoscopic Scoring Systems in Inflammatory Bowel Disease: Commentary Anna M. Buchner∙ Francis A. Farraye ∙ Marietta Iacucci Abstract…
AGA Clinical Practice Update on Endoscopic Enteral Access: Commentary Dejan Micic et al. Abstract Description The purpose of this American…
Use of artificial intelligence improves colonoscopy performance in adenoma detection: a systematic review and meta-analysis Jonathan Makar et al. Abstract…
Dietary management of irritable bowel syndrome: considerations, challenges, and solutions Kevin Whelan et al. Diet is a cornerstone in the…
Recent advances in clinical practice: mastering the challenge—managing IBS symptoms in IBD Judith Wellens et al. ABSTRACT Many patients with IBD…
Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis Kris V. Kowdley et al. Abstract Background Primary biliary cholangitis is…
Top-down infliximab plus azathioprine versus azathioprine alone in patients with acute severe ulcerative colitis responsive to intravenous steroids: a parallel,…
Primary biliary cholangitis Prof Atsushi Tanaka et al. Summary Primary biliary cholangitis is a chronic, autoimmune, cholestatic disease that mainly…
Primary drainage of distal malignant biliary obstruction: A comparative network meta-analysis Gaetano Lauri et al. Abstract Background The effectiveness of…
Do placebos harm patients in IBD trials? In 1955, Truelove and Witts published the first placebo-controlled, randomised clinical trial in…
Artificial intelligence and illusions of understanding in scientific research Lisa Messeri & M. J. Crockett Scientists are enthusiastically imagining ways in…
A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis Gideon M Hirschfield et al. Abstract Background: Effective treatments for patients…
MRI-guided stereotactic ablative body radiotherapy versus CT-guided percutaneous irreversible electroporation for locally advanced pancreatic cancer (CROSSFIRE): a single-centre, open-label, randomised…
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