ASPIRINA E RISCHIO CARDIOVASCOLARE. UNA NUOVA META-ANALISI PORTA IL RISCHIO DI EMORRAGIA DIGESTIVA A 21-98 CASI OGNI 10.000 PAZIENTI IN PIU’ RISPETTO AL CONTROLLO. DA “JACC: Advances” (FREE)

Aspirin With or Without Statin in Individuals Without Atherosclerotic Cardiovascular Disease Across Risk Categories Safi U. Khan et al   Abstract Background The effects of aspirin in adults without atherosclerotic cardiovascular disease (ASCVD), stratified by statin use across different ASCVD risks, remain uncertain. Objective To examine the effects of aspirin in adults without ASCVD, stratified by statin use across different…

RUOLO DEI BIOMARCATORI NELLA COLITE ULCEROSA. LE NUOVE LINEE GUIDA AGA. INSERITE ANCHE LA LATTOFERRINA FECALE! DA ” GASTROENTEROLOGY” (FREE)

AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis Siddharth Singh et al. Background & Aims Biomarkers are used frequently for noninvasive monitoring and treatment decision making in the management of patients with ulcerative colitis (UC). This American Gastroenterological Association (AGA) guideline is intended to support practitioners in decisions…

MALATTIA DI CROHN. LE LINEE GUIDA DEL GRUPPO IG-IBD APPENA USCITE! DA “Digestive and Liver Disease” (FREE)

Use of biologics for the management of Crohn’s disease: IG-IBD clinical guidelines based on the GRADE methodology FABIO MACALUSO ED Italian Group for the Study of Inflammatory Bowel Disease (IG-IBD) Abstract A cure for Crohn’s disease (CD), a chronic inflammatory disease of the gastrointestinal tract of unknown etiology, is not available, so patients require lifelong…

ONDANSETRON PER IL COLON IRRITABILE – DIARREA: IL TRIAL TRITON + META-ANALISI. BREAKING NEWS DA “ALIMENTARY PHARM & THERAP”

Randomised, Placebo-controlled Trial and Meta-analysis Show Benefit of Ondansetron for Irritable Bowel Syndrome with Diarrhoea: The TRITON Trial Gunn, David et al. Abstract Ondansetron may be beneficial in irritable bowel syndrome with diarrhoea (IBS-D). Aim: To conduct a 12-week parallel group, randomised, double-blind, placebo-controlled trial of ondansetron 4mg o.d. (titrated up to 8mg t.d.s.) in…

ENCEFALOPATIA EPATICA: UNA GRANDE META-ANALISI 2022 DALLA PARTE DEL PAZIENTE! LATTULOSIO O RIFAXIMINA? DA “AMERICAN JOURNAL OF GASTROENTEROLOGY”

Systematic Review and Meta-Analysis on the Effects of Lactulose and Rifaximin on Patient-Reported Outcomes in Hepatic Encephalopathy Andrew M. Moon et al INTRODUCTION: Patients with hepatic encephalopathy (HE) suffer from significant symptoms and impaired quality of life. Improved understanding on the potential benefits of first-line HE therapies may aid patientprovider discussions regarding expected benefits of…

LIVELLI EMATICI DI ENDOTOSSINA: BIOMARCATORI DELLA PROGRESSIONE DELLA NASH. UNA IMPEGNATIVA META-ANALISI DA “CLINICAL GASTROENTEROLOGY & HEPATOLOGY” (FREE).

Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease: a systematic review and meta-analysis Josefin Soppert et al. Abstract Background and Aims: Growing evidence supports a role of gut-derived metabolitesin non-alcoholic fatty liver disease (NAFLD), but the relation of endotoxin levels with gut permeability and NAFLD stage remains unclear. This systematic review with meta-…