RIFAXIMINA PER LA PREVENZIONE DELLA DIVERTICOLITE. LA EVIDENZA NON E’ ANCORA DEFINITIVA. UNA META-ANALISI DAL CLUB FOR EBG&H. DA “FRONTIERS IN GASTROENTEROLOGY” (FREE)

Preventing acute diverticulitis. any roles for non-absorbable antibiotics? in search of evidence: a systematic review, meta-analysis, and trial sequential analysis Maurizio Koch, Alberto Enrico Maraolo, Giuseppe Natoli3 and Salvatore Corrao Background: Hospital admissions for diverticulitis, a complication of diverticular disease, are very much on the increase. Prevention of diverticulitis could cut costs and save lives. Aims: To…

LA INTELLIGENZA ARTIFICIALE GPT-4 IN MEDICINA. BENEFICI E RISCHI. UN GRANDE ARTICOLO DAL “NEJM” CHE MERITA DA SOLO L’ABBONAMENTO

Benefits, Limits, and Risks of GPT-4 as an AI Chatbot for Medicine Peter Lee et al. The uses of artificial intelligence (AI) in medicine have been growing in many areas, including in the analysis of medical images,1 the detection of drug interactions,2 the identification of highrisk patients,3 and the coding of medical notes.4 Several such…

MALATTIA DIVERTICOLARE DOPO DIVERTICOLITE. RESEZIONE LAPAROSCOPICA SIGMOIDEA O TERAPIA CONSERVATIVA CON FIBRE (SENZA RIFA). UN OTTIMO TRIAL MULTICENTRICO DALLA FINLANDIA. “JAMA SURGERY” (FREE)

Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following DiverticulitisPrespecified 2-Year Analysis of the LASER Randomized Clinical Trial Alexandre Santos, et al. Key Points Question  Does sigmoid resection improve long-term quality of life of patients with recurring, complicated, or persistent painful diverticulitis compared to conservative treatment? Findings  In this prespecified 2-year follow-up of a randomized…

MICROBIOMA E CANCRO COLORETTALE. VERSO UNA GASTROENTEROLOGIA DI PRECISIONE? UN IMPORTANTE EDITORIALE DA” GASTROENTEROLOGY” (FREE)

Colorectal Cancer Subtyping With Microbiome—A Game Changer for Personalized Medicine? Chi Chun Wong, Jun Yu Colorectal cancer (CRC) was one of earliest solid tumors to be molecularly characterized, and the cascade of genetic events involved in the initiation and progression of CRC are well established.1 Advances in “omics” platforms encompassing genomic, epigenetic, transcriptomic, and immunologic…

GLI AGENTI CHE SEQUESTRANO GLI ACIDI BILIARI MIGLIORANO NETTAMENTE GLI ESITI CLINICI DELLA COLITE MICROSCOPICA ! UNO STUDIO DI COORTE SU 282 PAZIENTI DALLA MAYO. DA “Clinical Gastroenterology and Hepatology”

Bile Acid Sequestrants in Microscopic Colitis: Clinical Outcomes and Utility of Bile Acid Testing June Tome et al. Abstract BACKGROUND Bile acid sequestrants (BAS) may be a treatment in microscopic colitis (MC), but efficacy data are limited. We evaluated the effectiveness of BAS in MC and assessed the utility of bile acid testing to predict response.…

ATTENZIONE: UNO STUDIO DI REAL-WORLD ANALYSIS DALLA GERMANIA SUGGERISCE UN AUMENTO DELLA DEMENZA IN CHI USA CONTINUATIVAMENTE PPI. DA “DRUGS AGING”

Time-Varying Use of Proton Pump Inhibitors and Cognitive Impairment and Dementia: A Real-World Analysis from Germany Nayeon Ahn et al. Abstract Background: Cumulative evidence of dementia risk in patients taking proton pump inhibitors (PPIs) is still inconclusive, probably due to a variety of study designs. Objective: This study aimed to compare how the association between dementia risk…