MICROBIOTA E DISORDINI PSICHIATRICI: UNA GRANDE REVISIONE CON META-ANALISI

Perturbations in Gut Microbiota Composition in Psychiatric Disorders A Review and Meta-analysis Viktoriya L. Nikolova et al. IMPORTANCE Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions. OBJECTIVE…

I SOCIAL MEDIA STANNO DISTRUGGENDO UNA GENERAZIONE DI GIOVANI. UMAIR SU EUDAIMONIA&CO.

Social Media is Destroying a Generation of Young People — Especially Women If Anybody Else Did This to Young People, We’d Use Words Like Grooming, Abuse, and Pedophilia umair haque You see that chart above? It shows something that should deeply alarm you. Suicide rates have skyrocketed in young women and girls, since around 2009.…

ANCORA UN PASSO VERSO LA IMMORALITA’. DAL BMJ: ESITI SURROGATI E“ACCELERATED PATHWAYS” PER I FARMACI

The next step in immorality: charging to create and cure disease Kamran Abbasi executive editor “charge patients to become sick and be paid to help with treatment” Surrogate markers are seductive. In clinical trials and regulatory decisions, why not reach for something quick, convenient, and relatively cheap? Why stop patients receiving a treatment of plausible…

DAL “WASHINGTON POST” : 1 AMERICANO SU 500 E’ DECEDUTO PER COVID-19

The pandemic marks another grim milestone: 1 in 500 Americans have died of covid-19 By  Dan Keatin  , Akilah Johnson  and Monica Ulmanu   Updated Sept. 15 at 9:00 a.m.Originally published Sept. 15, 2021 At a certain point, it was no longer a matter of if the United States would reach the gruesome milestone of 1 in 500 people dying…

GASTROPARESI: EPIDEMIOLOGIA E TERAPIE DI REAL-WORLD EVIDENCE. UNO STUDIO SU GASTROENTEROLOGY DAL GRUPPO DI CAMILLERI

Epidemiology, etiology and treatment of gastroparesis: real-world evidence from a large US national claims database Y. Ye et al. Background & Aims While gastroparesis carries a considerable healthcare and patient burden, associated epidemiological data are limited. To provide new real-world evidence for gastroparesis, we estimated disease prevalence, and investigated patient demographics and disease etiology in…

LE NUOVE TERAPIE BIOLOGICHE E CON “SMALL MOLECULES” PER LE IBD. UNA GRANDE REVISIONE DAL NEJM

Newer Biologic and Small-Molecule Therapies for Inflammatory Bowel Disease Daniel C. Baumgart et al. Crohn’s disease and ulcerative colitis, together referred to as inflammatory bowel disease (IBD), are chronic systemic inflammatory disorders.1 These conditions target primarily the gastrointestinal tract but can affect many organ systems through extraintestinal manifestations (e.g., peripheral and axial arthritis, episcleritis, primary…