GEMELLI, IBD E MICROBIOMA: MARCATORI DELLA FLORA POTREBBERO PRECEDERE LA COMPARSA DELLE MANIFESTAZIONI CLINICHE

Healthy Cotwins Share Gut Microbiome Signatures With Their Inflammatory Bowel Disease Twins and Unrelated Patients Eelco C. Brand et al. Background & aims It is currently unclear whether reported changes in the gut microbiome are cause or consequence of inflammatory bowel disease (IBD). Therefore, we studied the gut microbiome of IBD-discordant and -concordant twin pairs, which offers the unique…

INTELLIGENZA ARTIFICIALE: QUALE GUADAGNO PER LA DIAGNOSI DI POLIPI IN COLONSCOPIA? L’EDITORIALE

Editorial Artificial intelligence for colonoscopy: the new Silk Road Alessandro Repici et al. It all began with a few hybrid information technology–medical studies claiming that a new type of software could recognize endoscopic lesions on offline images [1]. The use of the term “artificial intelligence” (AI) underlined how the learning process was driven by automatic…

INTELLIGENZA ARTIFICIALE: QUALE GUADAGNO PER LA DIAGNOSI DI POLIPI IN COLONSCOPIA? UNA OTTIMA META-ANALISI

Artificial intelligence for polyp detection during colonoscopy: a systematic review and meta-analysis Ishita Barua et al. Abstract Background Artificial intelligence (AI)-based polyp detection systems are used during colonoscopy with the aim of increasing lesion detection and improving colonoscopy quality. Patients and methods: We performed a systematic review and meta-analysis of prospective trials to determine the value of…

IL PLASMA DA CONVALESCENTI E’ DI DUBBIA UTILITA’ PER I PAZIENTI CON COVID-19. UNA META-ANALISI

Association of Convalescent Plasma Treatment With Clinical Outcomes in Patients With COVID-19A Systematic Review and Meta-analysis Perrine Janiaud et al. Key PointsQuestion  Is treatment with convalescent plasma associated with improved clinical outcomes? Findings  In a meta-analysis of 4 peer-reviewed and published randomized clinical trials including 1060 patients with COVID-19 treated with convalescent plasma vs control, the risk ratio…

DUE DECENNI DI RICERCA PER IL CANCRO DEL PANCREAS: QUALE GUADAGNO?

Two decades of research toward the treatment of locally advanced and metastatic pancreatic cancer: Remarkable effort and limited gain CelineYeh et al. Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that is diagnosed at the locally advanced or metastatic stage in approximately 80% of cases. Relative to other tumor types, progress in the treatment…