LA CERTEZZA DELLE EVIDENZE. UNA GUIDA DA “GRADE”

GRADE guidelines 32: GRADE offers guidance on choosing targets of GRADE certainty of evidence ratings Linan Zeng  et al. Abstract Objective To provide practical principles and examples to help GRADE users make optimal choices regarding their ratings of certainty of evidence using a minimally or partially contextualized approach. Study Design and Setting Based on the…

I TEST STATISTICI PER L’IPOTESI NULLA. QUALCOSA DA RICORDARE ?

Hypothesis Tests Explained Angelica Lo Duca A quick overview of the concept of Hypothesis Testing, its classification in parametric and non-parametric tests, and when to use the most popular ones. Image by Author What is Hypothesis Testing According to Jim Frost, Hypothesis Testing is a form of inferential statistics that allows us to draw conclusions about…

BUDESONIDE SPRAY PER COVID-19: RIDUZIONE DEL 2% DI RICOVERO O DECESSO NEL PAZIENTE A DOMICILIO A RISCHIO DI COMPLICANZE

Inhaled budesonide for COVID-19 in people at high risk of complications in the community in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial Ly-Mee Yu, et al. Summary Background A previous efficacy trial found benefit from inhaled budesonide for COVID-19 in patients not admitted to hospital, but effectiveness in high-risk individuals is unknown.…

STOP TERAPIA NUCLEOT(S)IDI NELL’EPATITE CRONICA HBeAg-NEGATIVA: OCCHIO AI RISCHI ! UN’OTTIMA META-ANALISI DA GUT

Discontinuation of nucleot(s)ide analogue therapy in HBeAg-negative chronic hepatitis B: a meta-analysis Samuel Anthony Lachlan Hall et al. Abstract Background and aims Sustained virological suppression and hepatitis B surface antigen (HBsAg) loss have been described after nucleot(s)ide analogue (NA) discontinuation for patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB). We performed a meta-analysis…

UN PORTALE PER “BUCARE” IL MURO DEL PAGAMENTO ED ARRIVARE ALLE PUBBLICAZIONI. DA QxMD

A portal to the papers beyond paywalls QxMD Bets are a paywall has stopped you from reading a paper at some point. Maybe that paper would have influenced your clinical practice? Saved a life? That might be a stretch, but there is significant evidence to suggest papers behind paywalls are viewed less and have less…