Surgical Management of Gastric Cancer. A Review George Z. Li et al. Abstract Importance Surgery plays a critical role in the management of all stages of gastric cancer. Observations For patients with early gastric cancer and low risk of lymph node metastasis, endoscopic therapy or surgery alone is potentially curative. Novel techniques, such as sentinel lymph node biopsy,…
Bill Gates explains “How to Prevent the Next Pandemic” His proposals for nipping infections in the bud are worth exploring How to Prevent the Next Pandemic. By Bill Gates. Knopf; 304 pages; $28. Allen Lane; £25 First, the climate. Next, plagues. Bill Gates’s career-switch from entrepreneur and philanthropist to crusading author is developing nicely. It is just over a year…
Algorithm-based care versus usual care for the early recognition and management of complications after pancreatic resection in the Netherlands: an open-label, nationwide, stepped-wedge cluster-randomised trial F Jasmijn Smits, MD et al. Summary Background Early recognition and management of postoperative complications, before they become clinically relevant, can improve postoperative outcomes for patients, especially for high-risk procedures…
The Gut-Lymph Model Gives New Treatment Strategies for Organ Failure John A. Windsor et al. Organ Failure Remains an Unmet Global Challenge Each year, more than 20 million people with organ failure (OF) are admitted to intensive care units around the world.1 With a 30% mortality rate, it remains the leading cause of death in intensive…
Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force Steven P. Dehmer et al. Abstract Importance The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC). Objective To provide…
USPSTF Report on Aspirin for Primary Prevention Donald M. Lloyd-Jones As with many therapies in modern medicine, aspirin for the primary prevention of atherosclerotic cardiovascular disease (ASCVD) is neither all good nor all bad. Specifically, aspirin may benefit selected patients, but that comes at the price of a narrower therapeutic window than desirable because of the…