BREAKING NEWS! IL PRIMO ANALGESICO NON-OPPIOIDE APPROVATO DALLA FOOD & DRUG AGENCY. E’ POTENTE. DA “NATURE” (FREE)

EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, INTERNATIONAL SNAPSHOTS, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NEWSLETTER, ONCOLOGIA, Senza categoria

US drug agency approves potent painkiller — the first non-opioid in decades The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels Elie Dolgin Researchers have long sought potent, but non-addictive, painkillers as alternatives to opioids.Credit: Getty When Terp Vairin awoke from a 2023 surgery that straightened a bend…

EFFICACIA E RISCHI DEGLI AGONISTI AI RECETTORI GLP-1. IL PIU’ GRANDE STUDIO RETROSPETTIVO AD OGGI (SOPRA 1,5 MILIONI PAZ) . LEGGETELO! DA”NATURE MEDICINE”

EPATOLOGIA, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, NEWSLETTER, NUTRIZIONE, ONCOLOGIA, Senza categoria

Mapping the effectiveness and risks of GLP-1 receptor agonists Yan Xie et al. Glucagon-like peptide 1 receptor agonists (GLP-1RAs) are increasingly being used to treat diabetes and obesity. However, their effectiveness and risks have not yet been systematically evaluated in a comprehensive set of possible health outcomes. Here, we used the US Department of Veterans…

METABOLIC DYSFUNCTION ASSOCIATED STEATOSIC LIVER DISEASE (MASLD). UN’OTTIMA REVISIONE IN DUE PAGINE ! DA “JAMA INTERNAL MEDICINE”

ECOGRAFIA ED ECOENDOSCOPIA, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, MEDICINA INTERNA, NEWSLETTER, Senza categoria

A Clinical Update on MASLD Grace Y. Zhang, MD; Danielle Brandman, MD, MAS Metabolic dysfunction–associated steatotic liver disease (MASLD; formerly nonalcoholic fatty liver disease) is a growing cause of chronic liver disease, affecting 25% of the population in the US and 30% of the population globally.  It is the second leading indication for liver transplant,…

APPENDICITE ACUTA DELL’ADULTO: ANTIBIOTICI vs CHIRURGIA. UNA OPZIONE PROPONIBILE. OTTIMA META-ANALISI SU DATI INDIVIDUALI. DA”THE LANCET GASTROENTEROLOGY & HEPATOLOGY”

CHIRURGIA, GASTROENTEROLOGIA, MEDICINA INTERNA, NEWSLETTER

Antibiotic treatment versus appendicectomy for acute appendicitis in adults: an individual patient data meta-analysis Jochem C G Scheijmans et al. Summary Background Randomised controlled trials (RCTs) have found antibiotics to be a feasible and safe alternative to appendicectomy in adults with imaging-confirmed acute appendicitis. However, patient inclusion criteria and outcome definitions vary greatly between RCTs. We…

ATTENZIONE ALL’INTELLIGENZA ARTIFICIALE IN MEDICINA! PRINCIPI DELL’USO DELLA IA PER LO SVILUPPO DI LINEE GUIDA. DA “ANNALS OF INTERNAL MEDICINE” (FREE)

GASTROENTEROLOGIA, MEDICINA INTERNA, METODOLOGIA, NEWSLETTER, Senza categoria

Guidelines International Network: Principles for Use of Artificial Intelligence in the Health Guideline Enterprise Bernardo Sousa-Pinto et al. Abstract Description: Artificial intelligence (AI) has been defined by the High-Level Expert Group on AI of the European Commission as “systems that display intelligent behaviour by analysing their environment and taking actions—with some degree of autonomy—to achieve…

GESTIONE DELLA TROMBOSI DELLA VENA PORTA. AGGIORNAMENTO DALL’AMERICAN GASTROENTEROLOGY ORGANIZATION FEBBRAIO 2025. “GASTROENTEROLOGY” (FREE)

CHIRURGIA, EPATOLOGIA, EPATOLOGIA ONCOLOGICA, GASTROENTEROLOGIA, NEWSLETTER, Senza categoria

AGA Clinical Practice Update on Management of Portal Vein Thrombosis in Patients With Cirrhosis: Expert Review Jessica P.E. Davis et al. Abstract Description Portal vein thromboses (PVTs) are common in patients with cirrhosis and are associated with advanced portal hypertension and mortality. The treatment of PVTs remains a clinical challenge due to limited evidence and competing…