VERSO UNA DISSEMINAZIONE DELLE EVIDENZE PIU’ RESPONSABILE. DA “BMJ EVIDENCE BASED MEDICINE” (FREE). IL PROBLEMA DEI PRESS RELASE.

Responsible dissemination of health and medical research: some guidance points Raffaella Ravinetto and Jerome Amir Singh Ravinetto and Singh argue that better practices can be implemented when disseminating research findings through abstracts, preprints, peer-reviewed publications, press releases and social media Dissemination has been defined as ‘the targeted distribution of information and intervention materials to a…

ALDACTONE CONTRO LA MALATTIA DA ABUSO DI ALCOL. UN NUOVO APPROCCIO ? INTERESSANTE. DA SEGUIRE!

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies Mehdi Farokhnia et al. Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR) antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may represent a novel pharmacotherapy for alcohol use disorder (AUD). In this study, we tested the effects…

DA DDW 2022. RIFAXIMINA: POOLED ANALYSIS DI 2 TRIAL NELLA IBS-D.

Rifaximin Effective for Multiple Symptoms in Irritable Bowel Syndrome With Diarrhea Colby Stong A 2-week course of rifaximin significantly improved multiple abdominal symptoms in patients with irritable bowel syndrome with diarrhea (IBS-D), according to study results presented at Digestive Disease Week (DDW), held from May 21 to 24, 2022, in San Diego, California, and virtually.…

UN CONSIGLIO: OCCHIO A COME USATE IL VALORE DELLA “P” ! DA “BMJ EVIDENCE BASED MEDICINE”.

Best way not to misuse p values is not to draw definitive conclusions about hypotheses David Trafimow et al. A recent article in BMJ Evidence-Based Medicine asserted the following1 , ‘We begin by saying that p values themselves are not flawed. Rather, the use, misuse or abuse of p values in ways antithetical to rigorous scientific…

PREVENZIONE DELLE INFEZIONI NEL CIRROTICO. UNA GRANDE REVIEW OPEN. DA “Semin Liver Dis” (FREE !). GUARDATE PER CREDERE!

Early Diagnosis and Prevention of Infections in Cirrhosis Anand V. Kulkarn et al. Abstract Strategies to prevent infection and improve outcomes in patients with cirrhosis. HAV, hepatitis A virus; HBV, hepatitis B virus; COVID-19, novel coronavirus disease 2019; NSBB, nonselective β-blocker; PPI, proton pump inhibitors. Cirrhosis is a risk factor for infections. Majority of hospital…

PERCHE’ FACEBOOK MINACCIA LA DEMOCRAZIA. IL GRANDE DISCORSO DELLA GIORNALISTA CADWALLADR DELL’OBSERVER (FREE).

Parola per parola, il formidabile discorso della giornalista che ha inchiodato Facebook Carole Cadwalladr. Presenta Riccardo Luna Quest’anno non sono riuscito ad andare al TED di Vancouver. Ma ho seguito qualcosa in rete. E mi hanno colpito due cose, collegate fra loro. La prima è il talk della giornalista dell’Observer che ha scoperchiato lo scandalo…