STOP AI PPI SE POSSIBILE ! RISCHIO PER MORTALITA’ DA COVID AUMENTATO. UNA META-ANALISI

COVID19 - EVIDENCE, GASTROENTEROLOGIA, MEDICI DI FAMIGLIA, MEDICINA INTERNA, REAL WORLD EVIDENCELascia un commento

Proton pump inhibitor on susceptibility to COVID-19 and its severity: a systematic review and meta-analysis Raymond Pranata et al. Abstract Background: The negative impacts of proton pump inhibitor (PPI), including the risk of pneumonia and mortality, have been reported previously. This meta-analysis aimed to address the current interest of whether the administration of PPI could increase…

RUOLO DELLA DIETA NELLA PREVENZIONE DELLE COMPLICAZIONI DELLA MALATTIA DIVERTICOLARE: UNA META-ANALISI DAI GASTROENTEROLOGI DEL S.ANDREA DI ROMA

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Role of Dietary Habits in the Prevention of Diverticular Disease Complications: A Systematic Review Marilia Carabotti et al. Abstract: Recent evidence showed that dietary habits play a role as risk factors for the development of diverticular complications. This systematic review aims to assess the effect of dietary habits in the prevention of diverticula complications (i.e.,…

VACCINI ANTI COVID E TROMBOSI. 5 DOMANDE: RISPONDE “NATURE”

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COVID vaccines and blood clots: five key questions As safety concerns delay the use of two COVID-19 vaccines, Nature looks at the questions that scientists want answered. Heidi Ledford It has been a difficult week for two COVID-19 vaccines. On 13 April, US regulators urged health-care providers to temporarily stop using a vaccine made by Johnson &…

BASTA RIFERIRE SOLO MISURE RELATIVE DI ESITI ! SONO POTENZIALMENTE CONFONDENTI! MEGLIO ASSOCIARE LE MISURE ASSOLUTE. E BASTA CON LE CIFRE DOPO LA VIRGOLA ! UNA RIFLESSIONE DAL GRUPPO DI STATISTICI DI BOLOGNA

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Reporting only relative effect measures was potentially misleading: some good practices for improving the soundness of epidemiological results Precision in reporting risk ratios Marco Novelli   Highlights • There is a growing tendency to report an excessive number of decimal digits; this can be misleading. • We combined statistical reasoning about the precision of relative risks…

LA TROMBOCITEMIA TROMBOTICA INDOTTA DAL VACCINO ANTI SARS-CoV-2. UNA ANALISI DEL NEJM

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SARS-CoV-2 Vaccine–Induced Immune Thrombotic Thrombocytopenia Douglas B. Cines, M.D., and James B. Bussel, M.D. The coronavirus disease 2019 (Covid-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulated the development of highly effective vaccines that were produced with unprecedented speed with the use of diverse technologies. No major safety warnings, other than rare…

ANTICOAGULANTI RIDUCONO LA MORTALITA PER COVID-19 OSPEDALIZZATI A DOSI PROFILATTICHE: LE DOSI TERAPEUTICHE AUMENTANO INVECE IL RISCHIO DI DECESSO. UNA META-ANALISI SU OLTRE 35.000 PAZIENTI

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Anticoagulation and In-Hospital Mortality From Coronavirus Disease 2019: A Systematic Review and Meta-Analysis Chatphatai Moonla, et al. Abstract Hypercoagulability in coronavirus disease 2019 (COVID-19) may aggravate disease severity during hospitalization but the reported survival benefits from anticoagulation (AC) vary among studies. We performed a literature research to estimate pooled odds ratios (ORs) of in-hospital mortality…