MARCATORI EMATICI DI PROGRESSIONE DI MALATTIA NELLE IBD. MEGLIO DELLA ENDOSCOPIA ? UNA IMPORTANTE CONFRONTO ISTOLOGIA-MARKERS EMATICI. DA”GUT”

Biopsy and blood-based molecular biomarker of inflammation in IBD Carmen Argmann et al ABSTRACT Objective IBD therapies and treatments are evolving to deeper levels of remission. Molecular measures of disease may augment current endpoints including the potential for less invasive assessments. Design Transcriptome analysis on 712 endoscopically defined inflamed (Inf) and 1778 non-inflamed (NonInf) intestinal biopsies…

STENOSI DELLE VIE BILIARI: L’ULTIMA MAGNIFICA REVISIONE DELL’AMERICAN COLLEGE OF GASTROENTEROLOGY. DA”AJG” (FREE)

ACG Clinical Guideline: Diagnosis and Management of Biliary Strictures Elmunzer, B. Joseph et al Abstract A biliary stricture is an abnormal narrowing in the ductal drainage system of the liver that can result in clinically and physiologically relevant obstruction to the flow of bile. The most common and ominous etiology is malignancy, underscoring the importance of a…

EPATITE DELTA: UNA GRANDE REVISIONE 2023 DA MARIO RIZZETTO. DA”NEW ENGLAND JOURNAL OF MEDICINE” (FREE)

Hepatitis D Virus Infection Tarik Asselah and Mario Rizzetto Hepatitis D virus (HDV), also known as hepatitis delta virus, is a defective, hepatotropic pathogenic agent. The life cycle of HDV requires the hepatitis B surface antigen (HBsAg) provided by hepatitis B virus (HBV).1 Like HBV, HDV is transmitted by the parenteral route through infectious body fluids;…

EMORRAGIA DIGESTIVA: LA POLVERE EMOSTATICA E’ NETTAMENTE SUPERIORE ALLA TERAPIA STANDARD ENDOSCOPICA NEL CANCRO GASTRICO! UN OTTIMO TRIAL MULTICENTRICO ASIATICO. DA”GASTROENTEROLOGY”

Hemostatic Powder vs Standard Endoscopic Treatment for Gastrointestinal Tumor Bleeding: A Multicenter Randomized Trial Rapat Pittayanon et al. Background & Aims Current guidelines vary as to their recommendations addressing the role of hemostatic powders when managing patients with malignant gastrointestinal (GI) bleeding because these are based on very-low- to low-quality evidence, in large part due to…

TRAPIANTO FECALE: LA PRIMA CONFERENZA INTERNAZIONALE PER TENTARE LA STANDARDIZZAZIONE DELLA TECNICA NELLE IBD ! FINALMENTE! DA”BMJ” (FREE)

The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease   Loris Riccardo Lopetuso et al. Abstract Background Several randomised clinical trials (RCTs) performing faecal microbiota transplantation (FMT) for the management of inflammatory bowel disease (IBD), particularly for ulcerative colitis, have recently been published, but with major variations in…

HCC: LA GESTIONE PERSONALIZZATA DEL PAZIENTE CON EPATOCARCINOMA, SECONDO AISF. UN NUOVO PARADIGMA! DA “The Lancet Oncology”

Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept Alessandro Vitale e HCC Special Interest Group of the Italian Association for the Study of the Liver. Summary Advances in the surgical and systemic therapeutic landscape of hepatocellular carcinoma have increased the complexity of patient management. A dynamic adaptation of the available staging-based algorithms…